Evidence map›Paper›PMID 27515057›Full record

ReviewAnnals of the rheumatic diseases2017

Consensus-based recommendations for the management of juvenile dermatomyositis.

Felicitas Bellutti Enders, Brigitte Bader-Meunier, Eileen Baildam, Tamas Constantin, Pavla Dolezalova, Brian M Feldman, Pekka Lahdenne, Bo Magnusson, Kiran Nistala, Seza Ozen and 11 more

Open access · bronzeAbstract readConsensus StatementReview
In one paragraph

Review in Annals of the rheumatic diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 3 pooled it
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 3 syntheses or guidelines pooled it, 309 citations in OpenAlex.

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53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 13 institutions in 12 countries.

Felicitas Bellutti EndersDepartment of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Brigitte Bader-MeunierDepartment for Immunology, Hematology and Pediatric Rheumatology, Necker Hospital, APHP, Institut IMAGINE, Paris, France.
Eileen BaildamAlder Hey Children's NHS Foundation Trust, Liverpool, UK.
Tamas Constantin2nd Department of Pediatrics, Semmelweis Hospital, Budapest, Hungary.
Pavla DolezalovaPaediatric Rheumatology Unit, Department of Paediatrics and Adolescent Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic.
Brian M FeldmanDivision of Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Pekka LahdenneDepartment of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland.
Bo MagnussonPaediatric Rheumatology Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital Stockholm, Sweden.
Kiran NistalaCentre for Adolescent Rheumatology, Institute of Child Health University College London, London, UK.
Seza OzenDepartment of Paediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Clarissa PilkingtonCentre for Adolescent Rheumatology, Institute of Child Health University College London, London, UK.
Angelo RavelliUniversità degli Studi di Genova and Istituto Giannina Gaslini, Genoa, Italy.
Ricardo RussoService of Immunology and Rheumatology, Hospital de Pediatría Garrahan, Buenos Aires, Argentina.
Yosef UzielDepartment of Paediatrics, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Marco van BrusselDivision of Pediatrics, Child Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
Janjaap van der NetDivision of Pediatrics, Child Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
Sebastiaan VastertDepartment of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Lucy R WedderburnCentre for Adolescent Rheumatology, Institute of Child Health University College London, London, UK.
Nicolaas WulffraatDepartment of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Liza J McCannAlder Hey Children's NHS Foundation Trust, Liverpool, UK.
Annet van Royen-KerkhofDepartment of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Wilhelmina Children's Hospital · NLUniversity College London · GBAlder Hey Children's NHS Foundation Trust · GBAssistance Publique – Hôpitaux de Paris · FRCharles University · CZGarrahan Hospital · ARHacettepe University · TRHelsinki University Hospital · FIIstituto Giannina Gaslini · ITKarolinska University Hospital · SEMeir Medical Center · ILSemmelweis University · HUSickKids Foundation · CA

Funding

Medical Research Council MR/N003322/1
6 · The paper itself

Abstract

backgroundIn 2012, a European initiative called Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) was launched to optimise and disseminate diagnostic and management regimens in Europe for children and young adults with rheumatic diseases. Juvenile dermatomyositis (JDM) is a rare disease within the group of paediatric rheumatic diseases (PRDs) and can lead to significant morbidity. Evidence-based guidelines are sparse and management is mostly based on physicians' experience. Consequently, treatment regimens differ throughout Europe.

objectivesTo provide recommendations for diagnosis and treatment of JDM.

methodsRecommendations were developed by an evidence-informed consensus process using the European League Against Rheumatism standard operating procedures. A committee was constituted, consisting of 19 experienced paediatric rheumatologists and 2 experts in paediatric exercise physiology and physical therapy, mainly from Europe. Recommendations derived from a validated systematic literature review were evaluated by an online survey and subsequently discussed at two consensus meetings using nominal group technique. Recommendations were accepted if >80% agreement was reached.

resultsIn total, 7 overarching principles, 33 recommendations on diagnosis and 19 recommendations on therapy were accepted with >80% agreement among experts. Topics covered include assessment of skin, muscle and major organ involvement and suggested treatment pathways.

conclusionsThe SHARE initiative aims to identify best practices for treatment of patients suffering from PRD. Within this remit, recommendations for the diagnosis and treatment of JDM have been formulated by an evidence-informed consensus process to produce a standard of care for patients with JDM throughout Europe.

Indexed as

Exercise TherapyCyclosporineDermatomyositisEuropeEvidence-Based MedicineGlucocorticoidsHumansImmunosuppressive AgentsMethotrexateMycophenolic AcidPatient Care TeamPrednisoloneRituximabSocieties, MedicalSunscreening AgentsCyclosporineGlucocorticoidsImmunosuppressive AgentsMethotrexateMycophenolic AcidPrednisoloneRituximabSunscreening AgentsAutoimmune DiseasesDermatomyositisTreatment

Identifiers

PMID27515057
PMCPMC5284351
OpenAlexW2517958812

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.