Evidence map›Paper›PMID 27514630›Full record

ArticleChild: care, health and development2016

The effects of caregiver and household HIV on child development: a community-based longitudinal study of young children.

L Sherr, S Skeen, I S Hensels, M Tomlinson, A Macedo

Open access · hybridAbstract read
In one paragraph

Article in Child: care, health and development, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

L SherrDepartment of Infection and Population Health, University College London, London, UK. l.sherr@ucl.ac.uk.
S SkeenDepartment of Psychology, Stellenbosch University, Stellenbosch, South Africa.
I S HenselsDepartment of Infection and Population Health, University College London, London, UK.
M TomlinsonDepartment of Psychology, Stellenbosch University, Stellenbosch, South Africa.
A MacedoDepartment of Infection and Population Health, University College London, London, UK.
Stellenbosch University · ZAUniversity College London · GBUniversity of Manchester · GB

Funding

Neighborhood Alcohol & HIV Prevention in South African TownshipsR01AA017104 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2007 to 2011
$3.8M
NIAAA NIH HHS R01 AA017104
6 · The paper itself

Abstract

objectiveMany studies that document child outcomes in the context of parental HIV - which has been established as a risk factor for child development - focus on older children/adolescents. Studies also concentrate on the status of the primary caregiver, not other household members who might be infected.

designThis study examined the effects of caregiver and household HIV on child development (4-13 years) in South Africa and Malawi (2011-2014).

methodsData were gathered from 989 children and their primary caregivers at baseline and repeated at 12-15 months follow-up (86.5% follow-up rate). Only caregivers of a single child and caregiver/child dyads without missing data were included, providing a sample of 808 dyads for analysis. Children were divided into three groups according to caregiver-reported HIV burden: having an HIV-positive primary caregiver (19.8%), having HIV in the household (14.2%) or no HIV (66%).

resultsThe HIV burden was positively associated with an array of negative child outcomes, often mediated by caregiver depression levels. Family HIV burden at baseline affected child behavioural problems at follow-up indirectly through carer depression (B = 0.02; CI = 0.003, 0.06). Internalizing (B = 0.02; CI = 0.002, 0.05) and externalizing problems at follow-up (B = 0.01; CI = 0.0002, 0.03) were also indirectly affected by family HIV burden through caregiver depression.

conclusionsThe data suggest that family HIV can affect child development, emphasizing the important role of depression in the pathway to such an effect. Community-based interventions directed at alleviating parental depression in the presence of HIV may help to interrupt the cycle of family HIV and adverse child outcomes.

Indexed as

AdolescentAdultAgedAged, 80 and overCaregiversChildChild Behavior DisordersChild DevelopmentChild of Impaired ParentsChild, PreschoolDepressionFamily HealthFemaleHealth Services AccessibilityHIV InfectionsHumanscaregiverschild developmentdepressionHIVviolence

Identifiers

PMID27514630
PMCPMC6086490
OpenAlexW2515009141

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.