ArticleBritish dental journal2016
A change in the NICE guidelines on antibiotic prophylaxis.
Article in British dental journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 61 citations in OpenAlex.
- Antibiotic Prophylaxis of Infective Endocarditis in Dentistry: An Update on the ESC, AHA, and NICE Guidelines.Journal of clinical medicine · 2026Review
- Antibiotic Prescribing in Dental Practice: A Cross-sectional Survey in Trinidad and Tobago.International dental journal · 2026Article
- Practice Variation in Infective Endocarditis Prophylaxis for Pediatric and Congenital Heart Disease Patients with Cardiac Implantable Electronic Devices: An International Survey.Pediatric cardiology · 2026Article
- Patient with Inflammatory Bowel Disease in a Dental Office-Which Antibiotic to Choose?-Narrative Review.Journal of clinical medicine · 2025Review
- Dental Antimicrobial Stewardship: Developing a Mobile Application for Rational Antibiotic Prescribing to Tackle Misdiagnosis.Antibiotics (Basel, Switzerland) · 2024Article
- Guideline for Perioperative Cardiovascular Evaluation of the Brazilian Society of Cardiology - 2024.Arquivos brasileiros de cardiologia · 2024Article
- Prevention of infective endocarditis in at-risk patients: how should dentists proceed in 2024?British dental journal · 2024Article
- Perception Regarding the NICE Guideline on Antibiotic Prophylaxis against Infective Endocarditis Following Dental Procedures: A Cross-Sectional Study.Antibiotics (Basel, Switzerland) · 2023Article
- Dental Management Considerations for Patients with Cardiovascular Disease-A Narrative Review.Reviews in cardiovascular medicine · 2022Review
- Infective endocarditis following invasive dental procedures: IDEA case-crossover study.Health technology assessment (Winchester, England) · 2022Observational
- Dentists' practice and compliance with current guidelines of infective endocarditis prophylaxis- National survey study.Journal of clinical and experimental dentistry · 2021Article
- Temporal Trends of Infective Endocarditis in Olmsted County, Minnesota, Between 1970 and 2018: A Population-Based Analysis.Open forum infectious diseases · 2021Article
- Involvement of Tunisian General Practitioners in the Management of Patients at Risk of Infective Endocarditis: A Cross-Sectional Study.International journal of dentistry · 2021Article
- Methicillin-ResistantInfectious diseases · 2020Review
- Evaluation of the Current Knowledge About Bacterial Endocarditis Prevention Among General Dentists in the City of Santo Domingo, Dominican Republic.Frontiers in public health · 2020Article
- Designing a customized clinical practice guideline regarding antibiotic prophylaxis for Iranian general dentists.BMC oral health · 2019Article
- Antibiotic prophylaxis for the prevention of infective endocarditis for dental procedures is not associated with fatal adverse drug reactions in France.Medicina oral, patologia oral y cirugia bucal · 2019Article
- [Non-cardiac surgery in adults with congenital heart defects : Most important parameters in anesthesia management].Der Anaesthesist · 2019Article
- Perioperative intervention by oral medicine team in cardiovascular surgery patients.General thoracic and cardiovascular surgery · 2019Review
- Has common sense prevailed?British dental journal · 2018Article
Corrections and comments
- Commented on by
Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since 2008, NICE clinical guidelines have stated: 'Antibiotic prophylaxis against infective endocarditis is not recommended for people undergoing dental procedures'. This put UK guidance at odds with guidance in the rest of the world, where antibiotic prophylaxis is recommended for patients at high-risk of infective endocarditis undergoing invasive dental procedures. Many dentists also felt this wording prohibited the use of antibiotic prophylaxis, regardless of the wishes of the patient or their personal risk of infective endocarditis and made it difficult for them to use their clinical judgment to deliver individualised care in the best interests of their patients. NICE have now changed this guidance to 'Antibiotic prophylaxis against infective endocarditis is not recommended routinely for people undergoing dental procedures.' This article examines the implications of this small but important change.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.