ReviewMicroscopy research and technique2017
Tip in-light on: Advantages, challenges, and applications of combining AFM and Raman microscopy on biological samples.
Review in Microscopy research and technique, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Rice straw sample preparation protocol for cell wall major constituent analysis via Raman spectroscopy.STAR protocols · 2026Article
- Atomic Force Microscopy Based Single Molecule Recognition: Deciphering Biological Interactions at the Nanoscale.Journal of molecular recognition : JMR · 2026Review
- Infrared Near-Field Microscopy as a Platform for Nanoscale Biomedical Spectroscopy and Imaging.ACS applied materials & interfaces · 2026Review
- Effects of different numbers of micro-osteoperforations on acceleration of orthodontic tooth movement and alveolar bone remodeling in rats.BMC oral health · 2026Article
- Atomic force microscopy at the forefront: unveiling foodborne viruses with biophysical tools.Npj viruses · 2025Review
- P-ring: The conserved nature of phosphorus enriched cells in seedling roots of distantly related species.Plant signaling & behavior · 2023Article
- Cell wall dynamics: novel tools and research questions.Journal of experimental botany · 2023Review
- Learning from Nature: Bacterial Spores as a Target for Current Technologies in Medicine (Review).Sovremennye tekhnologii v meditsine · 2021Review
- Wood Deformation Leads to Rearrangement of Molecules at the Nanoscale.Nano letters · 2020Article
- Correlated Materials Characterization via Multimodal Chemical and Functional Imaging.ACS nano · 2018Article
- New insights into plant cell walls by vibrational microspectroscopy.Applied spectroscopy reviews · 2018Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Scanning probe microscopies and spectroscopies, especially AFM and Confocal Raman microscopy are powerful tools to characterize biological materials. They are both non-destructive methods and reveal mechanical and chemical properties on the micro and nano-scale. In the last years the interest for increasing the lateral resolution of optical and spectral images has driven the development of new technologies that overcome the diffraction limit of light. The combination of AFM and Raman reaches resolutions of about 50-150 nm in near-field Raman and 1.7-50 nm in tip enhanced Raman spectroscopy (TERS) and both give a molecular information of the sample and the topography of the scanned surface. In this review, the mentioned approaches are introduced, the main advantages and problems for application on biological samples discussed and some examples for successful experiments given. Finally the potential of colocated AFM and Raman measurements is shown on a case study of cellulose-lignin films: the topography structures revealed by AFM can be related to a certain chemistry by the colocated Raman scan and additionally the mechanical properties be revealed by using the digital pulsed force mode. Microsc. Res. Tech. 80:30-40, 2017. © 2016 Wiley Periodicals, Inc.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.