Trial reportPloS one2016
Long Term Effects on Risk Factors for Cardiovascular Disease after 12-Months of Aerobic Exercise Intervention - A Worksite RCT among Cleaners.
Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Associations of working conditions and chronic low-grade inflammation among employees: a systematic review and meta-analysis.Scandinavian journal of work, environment & health · 2021Pooled it
- Effects of Physical Exercise Training in the Workplace on Physical Fitness: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- Occupational Physical Activity and Hypertension: A Narrative Review.Current hypertension reports · 2026Review
- The physical activity health paradox: what is it, why might it happen, and where to go from here?The international journal of behavioral nutrition and physical activity · 2026Review
- Cardiovascular load and physical capacity in older workers engaged in physically demanding occupations.International archives of occupational and environmental health · 2025Article
- Factors associated with blue-collar workers' participation in Worksite Health Promotion Programs: a scoping literature review.Health promotion international · 2023Article
- Hypertension in Workers: The Role of Physical Activity and its Different Dimensions.Arquivos brasileiros de cardiologia · 2020Article
- Factors associated with musculoskeletal symptoms and heart rate variability among cleaners - cross-sectional study.BMC public health · 2020Article
- Physical workload and obesity have a synergistic effect on work ability among construction workers.International archives of occupational and environmental health · 2019Article
- Effects of Exercise on the Resting Heart Rate: A Systematic Review and Meta-Analysis of Interventional Studies.Journal of clinical medicine · 2018Review
- Physical Activity as Cause and Cure of Muscular Pain: Evidence of Underlying Mechanisms.Exercise and sport sciences reviews · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesOccupational groups exposed to high occupational physical activity have an increased risk for cardiovascular disease (CVD). This may be explained by the high relative aerobic workload. Enhanced cardiorespiratory fitness reduces the relative aerobic workload. Thus, the aim was to evaluate the 12-months effects of worksite aerobic exercise on risk factors for CVD among cleaners.
methodsOne hundred and sixteen cleaners aged 18-65 years were randomized to a group performing aerobic exercise and a reference group receiving lectures. Outcomes were collected at baseline and after 12-months. A repeated measures 2×2 multi-adjusted mixed-model design was applied to compare the between-group differences using intention-to-treat analysis.
resultsBetween-group differences (p<0.05) were found favouring the aerobic exercise group: cardiorespiratory fitness 2.15 (SE 1.03) mlO2/min/kg, aerobic workload -2.15 (SE 1.06) %HRR, resting HR -5.31 (SE 1.61) beats/min, high sensitive C-reactive protein -0.65 (SE 0.24) μg/ml. The blood pressure was unaltered. Stratified analyses on relative aerobic workload at baseline revealed that those with relative aerobic workloads ≥30% of HRR seems to impose a notable adverse effect on resting and ambulatory blood pressure.
conclusionThis long-term worksite aerobic exercise intervention among cleaners led to several beneficial effects, but also potential adverse effects among those with high relative aerobic workloads.
trial registrationControlled-Trials.com ISRCTN86682076.
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