Evidence map›Paper›PMID 27513765›Full record

ReviewThe Journal of craniofacial surgery2016

Clinical Considerations for Vascularized Composite Allotransplantation of the Eye.

Edward H Davidson, Eric W Wang, Jenny Y Yu, Juan C Fernandez-Miranda, Dawn J Wang, Yang Li, Maxine Miller, Wesley N Sivak, Debra Bourne, Hongkun Wang and 3 more

Abstract readReview
In one paragraph

Review in The Journal of craniofacial surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Monitoring outcomes of the first human whole eye allotransplant.Documenta ophthalmologica. Advances in ophthalmology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Edward H Davidson*Department of Plastic Surgery †Department of Otolaryngology ‡Department of Ophthalmology §Department of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA ||Department of Plastic and Reconstructive Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China ¶Pittsburgh VA Healthcare System, Pittsburgh, PA.
Eric W Wang
Jenny Y Yu
Juan C Fernandez-Miranda
Dawn J Wang
Yang Li
Maxine Miller
Wesley N Sivak
Debra Bourne
Hongkun Wang
Mario G Solari
Joel S Schuman
Kia M Washington

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ethan A Rossi · 1989 to 2026
$17.8M
Novel Glaucoma Diagnostics for Structure and Function - Renewal - 1R01EY013178 · NEI · WILLS EYE HEALTH SYSTEM · PI Joel S Schuman · 2000 to 2026
$17.5M
NEI NIH HHS P30 EY008098NEI NIH HHS R01 EY013178
6 · The paper itself

Abstract

Vascularized composite allotransplantation represents a potential shift in approaches to reconstruction of complex defects resulting from congenital differences as well as trauma and other acquired pathology. Given the highly specialized function of the eye and its unique anatomical components, vascularized composite allotransplantation of the eye is an appealing method for restoration, replacement, and reconstruction of the nonfunctioning eye. Herein, we describe conventional treatments for eye restoration and their shortcomings as well as recent research and events that have brought eye transplantation closer to a potential clinical reality. In this article, we outline some potential considerations in patient selection, donor facial tissue procurement, eye tissue implantation, surgical procedure, and potential for functional outcomes.

Indexed as

AnimalsBlindnessEyeHumansPatient SelectionPostoperative CareRatsTissue and Organ HarvestingTissue and Organ ProcurementVascularized Composite Allotransplantation

Identifiers

PMID27513765
PMCPMC5342906

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.