ArticleJournal of neurochemistry2016
Cannabinoid receptor interacting protein suppresses agonist-driven CB
Open access · greenAbstract read
In one paragraph
Article in Journal of neurochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- The primary somatosensory sensory cortex-basolateral amygdala pathway contributes to comorbid depression in spared nerve injury-induced neuropathic pain.Scientific reports · 2025Article
- Presynaptic nanoscale components of retrograde synaptic signaling.Science advances · 2024Article
- Mechanisms of cannabinoid tolerance.Biochemical pharmacology · 2023Review
- Functional Selectivity of a Biased Cannabinoid-1 Receptor (CBACS pharmacology & translational science · 2021Article
- Targeting Endocannabinoid Signaling in the Lateral Habenula as an Intervention to Prevent Mental Illnesses Following Early Life Stress: A Perspective.Frontiers in synaptic neuroscience · 2021Article
- Cannabinoid Receptor Interacting Protein 1a (CRIP1a) in Health and Disease.Biomolecules · 2020Review
- Article
- Protein Interactors and Trafficking Pathways That Regulate the Cannabinoid Type 1 Receptor (CB1R).Frontiers in molecular neuroscience · 2020Review
- Molecular Interaction between Distal C-Terminal Domain of the CBJournal of chemical information and modeling · 2019Article
- Cannabinoid Receptor Interacting Protein 1a (CRIP1a): Function and Structure.Molecules (Basel, Switzerland) · 2019Review
- Structural Insights into CB1 Receptor Biased Signaling.International journal of molecular sciences · 2019Review
- In silico interaction analysis of cannabinoid receptor interacting protein 1b (CRIP1b) - CB1 cannabinoid receptor.Journal of molecular graphics & modelling · 2017Article
- The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility.Scientific reports · 2017Article
- Cannabinoid Receptor Interacting Protein 1a Competition with β-Arrestin for CB1 Receptor Binding Sites.Molecular pharmacology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Lawrence C BlumeDepartment of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.
Sandra Leone-KablerDepartment of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.
Deborah J LuessenDepartment of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.
Glen S MarrsDepartment of Biology, Wake Forest University, Winston-Salem, North Carolina, USA.
Erica LyonsDepartment of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.
Caroline E BassDepartment of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.
Rong ChenDepartment of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.
Dana E SelleyDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
Allyn C HowlettDepartment of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA. ahowlett@wakehealth.edu.
Wake Forest University · USVirginia Commonwealth University · US
Funding
MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISMT32AA007565 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRIAN A MCCOOL · 1994 to 2026
$10.1MCANNABINOID RECEPTORS IN NEURONAL CELLS AND BRAINR01DA003690 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOWLETT, ALLYN C · 1985 to 2014
$2.8MNEUROSCIENCE OF DRUG ABUSE TRAINING PROGRAMT32DA007246 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHILDERS, STEVEN R · 1991 to 2011
$2.2MIntegrative Lipid Metabolism, Inflammation, and Chronic DiseasesT32HL091797 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PARKS, JOHN S · 2008 to 2017
$1.8MCB1 and DA Receptor Deletion by RNAi in Cocaine Self-AdministrationK01DA024763 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BASS, CAROLINE EVELYN · 2008 to 2011
$568kCB1 Receptor Regulation by Cannabinoid Receptor Interacting Protein CRIP1aR21DA025321 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI HOWLETT, ALLYN C, SELLEY, DANA E · 2009 to 2010
$420kFunctional studies of cannabinoid receptor-interacting protein 1a in null miceR03DA035424 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI SELLEY, DANA E · 2014 to 2015
$151kCannabinoid Receptor Interacting Protein1a Structure-FunctionF31DA032215 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BLUME, LAWRENCE CHRISTOPHER · 2012 to 2013
$83kNHLBI NIH HHS T32 HL091797NIAAA NIH HHS T32 AA007565NIDA NIH HHS F31 DA032215NIDA NIH HHS K01 DA024763NIDA NIH HHS R01 DA003690NIDA NIH HHS R03 DA035424NIDA NIH HHS R21 DA025321NIDA NIH HHS T32 DA007246
Abstract
Cannabinoid receptor interacting protein 1a (CRIP1a) is a CB
Indexed as
AnimalsBenzoxazinesCarrier ProteinsCell LineCell MembraneCyclohexanolsEndocannabinoidsGene DosageGene Knockdown TechniquesMiceMorpholinesNaphthalenesPiperidinesProtein TransportPyrazolesReceptor, Cannabinoid, CB13-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanoneBenzoxazinesCarrier ProteinsCRIP1a protein, mouseCyclohexanolsEndocannabinoidsMorpholinesNaphthalenesPiperidinesPyrazolesReceptor, Cannabinoid, CB1Receptors, Cell SurfaceRimonabantRNA, Small Interferingcannabinoid receptor interacting proteinCB1 cannabinoid receptorCP55940receptor traffickingrimonabantWIN55212-2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.