Evidence map›Paper›PMID 27513600›Full record

Trial reportPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2016

Utilizing a Collaborative Learning Model to Promote Early Extubation Following Infant Heart Surgery.

William T Mahle, Susan C Nicolson, Danielle Hollenbeck-Pringle, Michael G Gaies, Madolin K Witte, Eva K Lee, Michelle Goldsworthy, Paul C Stark, Kristin M Burns, Mark A Scheurer and 7 more

Erratum issuedOpen access · greenAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
26.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Early extubation after pediatric cardiac surgery.Anesthesia and pain medicine · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Comparison of outcomes of pulmonary valve replacement in adult versus paediatric hospitals: institutional influence†.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2019
    Article
  12. Changes in Anesthetic and Postoperative Sedation-Analgesia Practice Associated With Early Extubation Following Infant Cardiac Surgery: Experience From the Pediatric Heart Network Collaborative Learning Study.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019
    Article
  13. Review
  14. Extubation Failure Rates After Pediatric Cardiac Surgery Vary Across Hospitals.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2018
    Observational
  19. Article
  20. Characteristics, Risk Factors, and Outcomes of Extracorporeal Membrane Oxygenation Use in Pediatric Cardiac ICUs: A Report From the Pediatric Cardiac Critical Care Consortium Registry.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 2 countries.

William T Mahle1Department of Pediatrics, Emory University, Atlanta, GA.2Department of Anesthesia, Children's Hospital of Philadelphia, Philadelphia, PA.3New England Research Institutes, Watertown, MA.4Department of Pediatrics, University of Michigan, Ann Arbor, MI.5Department of Pediatrics, University of Utah, Salt Lake City, UT.6Industrial Engineering Department, Georgia Institute of Technology, Atlanta, GA.7Department of Pediatrics, Baylor College of Medicine, Houston, TX.8National Heart, Lung, and Blood Institute, Bethesda, MD.9Department of Pediatrics, Medical University of South Carolina, Charleston, SC.10Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH.11Cardiology Department, Boston Children's Hospital, Boston, MA.12Department of Critical Care Medicine, Hospital for Sick Children, Toronto, ON, Canada.13Department of Pediatrics, Riley Children's Hospital, Indianapolis, IN.
Susan C Nicolson
Danielle Hollenbeck-Pringle
Michael G Gaies
Madolin K Witte
Eva K Lee
Michelle Goldsworthy
Paul C Stark
Kristin M Burns
Mark A Scheurer
David S Cooper
Ravi Thiagarajan
V Ben Sivarajan
Steven D Colan
Marcus S Schamberger
Lara S Shekerdemian
Pediatric Heart Network Investigators
Baylor College of Medicine · USNew England Research Institutes · USCincinnati Children's Hospital Medical Center · USEmory University · USHospital for Sick Children · CAMedical University of South Carolina · USNational Heart Lung and Blood Institute · USRiley Hospital for Children · USUniversity of Michigan–Ann Arbor · USUniversity of Utah · US

Funding

Pediatric Heart network DCCU10HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MILLER, JULIE ELAINE, TRACHTENBERG, FELICIA LYNN · 2011 to 2016
$44.9M
Ventricular Volumes and Varability (VVV)U01HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI SLEEPER, LYNN A · 2001 to 2010
$40.3M
Sidenafil Impacts Exercise Performance in Adolescent Survivors of the FontanU10HL109818 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI GAYNOR, JAMES WILLIAM, PARIDON, STEPHEN · 2011 to 2015
$2.7M
Randomized Trial of Nonflouroscopic Technologies in Pediatric SVT AblationU10HL109816 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI NEWBURGER, JANE W., TRIEDMAN, JOHN K · 2011 to 2015
$2.6M
Pediatric Heart Network Prairieland ConsortiumU10HL109673 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI CNOTA, JAMES, PAYNE, RONALD MARK · 2011 to 2015
$2.3M
Pediatric Heart Network Regents of the University of MichiganU10HL109737 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GOLDBERG, CAREN S, OHYE, RICHARD G · 2011 to 2015
$2.3M
Pediatric Heart Network University of UtahU10HL109743 · NHLBI · UNIVERSITY OF UTAH · PI MINICH, L. LUANN, WILLIAMS, RICHARD VINCENT · 2011 to 2015
$2.2M
Pediatric Heart Network Emory UniversityUG1HL135682 · NHLBI · EMORY UNIVERSITY · PI BOOK, WENDY M., KOCHILAS, LAZAROS K. · 2017 to 2023
$2.2M
Pediatric Heart Network Medical University of South CarolinaU10HL109778 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ATZ, ANDREW M, GRAHAM, ERIC M. · 2011 to 2015
$2.2M
Baylor/Texas Children's Hospital Pediatric Heart NetworkU10HL109741 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI ANDROPOULOS, DEAN B., FRASER, CHARLES D. · 2011 to 2015
$2.1M
Pediatric Heart Network Emory UniversityU10HL109781 · NHLBI · EMORY UNIVERSITY · PI BORDER, WILLIAM, MAHLE, WILLIAM T · 2011 to 2015
$1.7M
Pediatric Heart Network - The Hospital for Sick Children, TorontoU10HL109777 · NHLBI · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI MCCRINDLE, BRIAN W, MITAL, SEEMA · 2011 to 2015
$1.6M
NHLBI NIH HHS U01 HL068270NHLBI NIH HHS U10 HL068270NHLBI NIH HHS U10 HL109673NHLBI NIH HHS U10 HL109737NHLBI NIH HHS U10 HL109741NHLBI NIH HHS U10 HL109743NHLBI NIH HHS U10 HL109777NHLBI NIH HHS U10 HL109778NHLBI NIH HHS U10 HL109781NHLBI NIH HHS U10 HL109816NHLBI NIH HHS U10 HL109818NHLBI NIH HHS UG1 HL135682
6 · The paper itself

Abstract

objectiveTo determine whether a collaborative learning strategy-derived clinical practice guideline can reduce the duration of endotracheal intubation following infant heart surgery.

designProspective and retrospective data collected from the Pediatric Heart Network in the 12 months pre- and post-clinical practice guideline implementation at the four sites participating in the collaborative (active sites) compared with data from five Pediatric Heart Network centers not participating in collaborative learning (control sites).

settingTen children's hospitals. PATIENTS: Data were collected for infants following two-index operations: 1) repair of isolated coarctation of the aorta (birth to 365 d) and 2) repair of tetralogy of Fallot (29-365 d). There were 240 subjects eligible for the clinical practice guideline at active sites and 259 subjects at control sites.

interventionsDevelopment and application of early extubation clinical practice guideline. MEASUREMENTS AND MAIN

resultsAfter clinical practice guideline implementation, the rate of early extubation at active sites increased significantly from 11.7% to 66.9% (p < 0.001) with no increase in reintubation rate. The median duration of postoperative intubation among active sites decreased from 21.2 to 4.5 hours (p < 0.001). No statistically significant change in early extubation rates was found in the control sites 11.7% to 13.7% (p = 0.63). At active sites, clinical practice guideline implementation had no statistically significant impact on median ICU length of stay (71.9 hr pre- vs 69.2 hr postimplementation; p = 0.29) for the entire cohort. There was a trend toward shorter ICU length of stay in the tetralogy of Fallot subgroup (71.6 hr pre- vs 54.2 hr postimplementation, p = 0.068).

conclusionsA collaborative learning strategy designed clinical practice guideline significantly increased the rate of early extubation with no change in the rate of reintubation. The early extubation clinical practice guideline did not significantly change postoperative ICU length of stay.

Indexed as

Cardiac Surgical ProceduresCooperative BehaviorIntubation, IntratrachealLearningPractice Guidelines as TopicAirway ExtubationHospitals, PediatricHumansInfantInfant, NewbornIntensive Care Units, PediatricLength of StayModels, OrganizationalProspective StudiesQuality ImprovementRetrospective Studies

Identifiers

PMID27513600
PMCPMC5053873
OpenAlexW2517300525

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.