ArticlePloS one2016
Disparities in Depressive Symptoms and Antidepressant Treatment by Gender and Race/Ethnicity among People Living with HIV in the United States.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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Who cites it
35 citing papers in PubMed, 52 citations in OpenAlex.
- Gender differences among criminal justice-involved persons living with HIV interested in extended-release naltrexone treatment.Substance abuse · 2021Trial
- Routine collection of patient-reported outcomes in HIV clinics: lessons learned after more than 130 000 assessments have been completed.AIDS (London, England) · 2026Article
- The kynurenine pathway in relation to depression and anhedonia symptom severity among women with HIV.Brain, behavior, & immunity - health · 2026Article
- Review
- Sociodemographic and clinical factors associated with use of depression treatment among people with HIV in the United States: An electronic health records-based cohort study.Journal of affective disorders · 2025Article
- The Assessment of the Safety Profile of Selective Serotonin Reuptake Inhibitors Versus Other Antidepressants: Drug-Drug Interaction Insights from EudraVigilance.Journal of clinical medicine · 2025Article
- Impact of a psychoeducational intervention on willingness to seek help for depression among African American young adults.Transcultural psychiatry · 2024Article
- Lessons Learned from a Community-led, Pilot Teletherapy Group for Older Women Living with Depression and HIV.AIDS and behavior · 2024Article
- Latent Profile Analysis of Cognitive Performance and Depressive Symptoms Among People with HIV.AIDS patient care and STDs · 2024Article
- Depressive Symptoms, the Impact on ART Continuation, and Factors Associated with Symptom Improvement Among a Cohort of People Living with HIV in British Columbia, Canada.AIDS and behavior · 2024Article
- Racial, ethnic, and age disparities in the association of mental health symptoms and polysubstance use among persons in HIV care.PloS one · 2023Article
- A Bayesian nonparametric approach for inferring drug combination effects on mental health in people with HIV.Biometrics · 2022Article
- Prevalence of depression and associated factors among people living with HIV/AIDS in public hospitals of Southeast Ethiopia.BMC psychiatry · 2022Article
- Depressive Symptoms, Gender, Disclosure, and HIV Care Stage Among People Living with HIV in Cameroon.AIDS and behavior · 2022Article
- BAGEL: A BAYESIAN GRAPHICAL MODEL FOR INFERRING DRUG EFFECT LONGITUDINALLY ON DEPRESSION IN PEOPLE WITH HIV.The annals of applied statistics · 2022Article
- Depression and Associated Factors Among Men Living with HIV/AIDS Aged 50 Years and Over in Chongqing, China.Journal of multidisciplinary healthcare · 2022Article
- Recruitment and Retention of Women Living With HIV for Clinical Research: A Review.AIDS and behavior · 2021Review
- The Patient Reported Outcomes as a Clinical Tool (PROACT) Pilot Study: What Can be Gained by Sharing Computerized Patient-Reported Mental Health and Substance Use Symptoms with Providers in HIV Care?AIDS and behavior · 2021Article
- Social inequalities contribute to racial/ethnic disparities in depressive symptomology among men who have sex with men.Social psychiatry and psychiatric epidemiology · 2021Article
- Mental Health Screening Practices Among Primary Care Providers in High HIV Burden Areas of the South: Does Having Patients with HIV Matter?The journal of behavioral health services & research · 2021Article
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 1 country.
Funding
Abstract
objectiveTo describe disparities along the depression treatment cascade, from indication for antidepressant treatment to effective treatment, in HIV-infected individuals by gender and race/ethnicity.
methodsThe Center for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS) cohort includes 31,000 HIV-infected adults in routine clinical care at 8 sites. Individuals were included in the analysis if they had a depressive symptoms measure within one month of establishing HIV care at a CNICS site. Depressive symptoms were measured using the validated Patient Health Questionnaire-9 (PHQ-9). Indication for antidepressant treatment was defined as PHQ-9 ≥ 10 or a current antidepressant prescription. Antidepressant treatment was defined as a current antidepressant prescription. Evidence-based antidepressant treatment was considered treatment changes based on a person's most recent PHQ-9, in accordance with clinical guidelines. We calculated the cumulative probability of moving through the depression treatment cascade within 24 months of entering CNICS HIV care. We used multivariable Cox proportional hazards models to estimate associations between gender, race/ethnicity, and a range of depression outcomes.
resultsIn our cohort of HIV-infected adults in routine care, 47% had an indication for antidepressant treatment. Significant drop-offs along the depression treatment cascade were seen for the entire study sample. However, important disparities existed. Women were more likely to have an indication for antidepressant treatment (HR 1.54; 95% CI 1.34, 1.78), receive antidepressant treatment (HR 2.03; 95% CI 1.53, 2.69) and receive evidence-based antidepressant treatment (HR 1.67; 95% CI 1.03, 2.74), even after accounting for race/ethnicity. Black non-Hispanics (HR 0.47, 95% CI 0.35, 0.65), Hispanics (HR 0.63, 95% CI 0.44, 0.89) and other race/ethnicities (HR 0.35, 95% CI 0.17, 0.73) were less likely to initiate antidepressant treatment, compared to white non-Hispanics.
conclusionsIn our cohort of HIV-infected adults depressive symptoms were common. Important disparities in the prevalence of depressive symptoms and receipt of antidepressant treatment existed by gender and race/ethnicity.
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