ArticlePLoS genetics2016
Combating a Global Threat to a Clonal Crop: Banana Black Sigatoka Pathogen Pseudocercospora fijiensis (Synonym Mycosphaerella fijiensis) Genomes Reveal Clues for Disease Control.
Article in PLoS genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 49 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic Improvement for Resistance to Black Sigatoka in Bananas: A Systematic Review.Frontiers in plant science · 2021Pooled it
- The dual role of azoles: lifesaving antifungals and drivers of resistance - a One Health perspective.Nature communications · 2026Review
- Massive proliferation of retrotransposons contributes to genome size expansion in species of the Pseudocercospora genus.Mobile DNA · 2026Article
- Chromosome-scale Genome Assembly of the Most Abundant Ectomycorrhizal Fungus Cenococcum Geophilum Reveals Massive TE Expansion and RIP Defense Mechanism.Genome biology and evolution · 2026Article
- Shaping the future of bananas: advancing genetic trait regulation and breeding in the postgenomics era.Horticulture research · 2025Article
- Expression of Genes Involved in Banana (Current issues in molecular biology · 2024Article
- Precision genetics tools for genetic improvement of banana.The plant genome · 2024Review
- A chromosome-level genome assembly of Zasmidium syzygii isolated from banana leaves.G3 (Bethesda, Md.) · 2024Article
- Application of CRISPR/Cas-based gene-editing for developing better banana.Frontiers in bioengineering and biotechnology · 2024Review
- Pan-genome survey ofFrontiers in microbiology · 2024Article
- Comparative genomics of the extremophileFrontiers in fungal biology · 2024Article
- GC-MS metabolite profiling of Pseudocercospora fijiensis isolates resistant to thiabendazole.PloS one · 2024Article
- Article
- Metapangenomics of wild and cultivated banana microbiome reveals a plethora of host-associated protective functions.Environmental microbiome · 2023Article
- Article
- Transcriptome Profiling of the Resistance Response ofInternational journal of molecular sciences · 2022Article
- The BananaGenes · 2022Article
- Gene Expression, Histology and Histochemistry in the Interaction betweenPlants (Basel, Switzerland) · 2022Article
- Genome-Wide Analysis of theGenes · 2022Article
- Genetic Characteristics and Metabolic Interactions betweenPlants (Basel, Switzerland) · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
30 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Black Sigatoka or black leaf streak disease, caused by the Dothideomycete fungus Pseudocercospora fijiensis (previously: Mycosphaerella fijiensis), is the most significant foliar disease of banana worldwide. Due to the lack of effective host resistance, management of this disease requires frequent fungicide applications, which greatly increase the economic and environmental costs to produce banana. Weekly applications in most banana plantations lead to rapid evolution of fungicide-resistant strains within populations causing disease-control failures throughout the world. Given its extremely high economic importance, two strains of P. fijiensis were sequenced and assembled with the aid of a new genetic linkage map. The 74-Mb genome of P. fijiensis is massively expanded by LTR retrotransposons, making it the largest genome within the Dothideomycetes. Melting-curve assays suggest that the genomes of two closely related members of the Sigatoka disease complex, P. eumusae and P. musae, also are expanded. Electrophoretic karyotyping and analyses of molecular markers in P. fijiensis field populations showed chromosome-length polymorphisms and high genetic diversity. Genetic differentiation was also detected using neutral markers, suggesting strong selection with limited gene flow at the studied geographic scale. Frequencies of fungicide resistance in fungicide-treated plantations were much higher than those in untreated wild-type P. fijiensis populations. A homologue of the Cladosporium fulvum Avr4 effector, PfAvr4, was identified in the P. fijiensis genome. Infiltration of the purified PfAVR4 protein into leaves of the resistant banana variety Calcutta 4 resulted in a hypersensitive-like response. This result suggests that Calcutta 4 could carry an unknown resistance gene recognizing PfAVR4. Besides adding to our understanding of the overall Dothideomycete genome structures, the P. fijiensis genome will aid in developing fungicide treatment schedules to combat this pathogen and in improving the efficiency of banana breeding programs.
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