Evidence map›Paper›PMID 27512901›Full record

ReviewCell host & microbe2016

Bacterial Stress Responses during Host Infection.

Ferric C Fang, Elaine R Frawley, Timothy Tapscott, Andrés Vázquez-Torres

Abstract readReview
In one paragraph

Review in Cell host & microbe, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 188 papers.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed.

  1. Article
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  9. Review
  10. The critical role ofApplied and environmental microbiology · 2026
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  16. Review
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128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ferric C FangDepartment of Microbiology, University of Washington School of Medicine, Seattle, WA 98195-7735, USA; Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195-7735, USA. Electronic address: fcfang@uw.edu.
Elaine R FrawleyDepartment of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195-7735, USA.
Timothy TapscottDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Andrés Vázquez-TorresDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

Funding

Salmonella evasion of NADPH oxidase-dependent killingR01AI054959 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2003 to 2018
$5.2M
THE SALMONELLA TYPHIMURIUM SIGMAE REGULONR01AI044486 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 1999 to 2016
$4.9M
NITRIC OXIDE CYTOTOXICITY IN SALMONELLOSISR01AI039557 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 1997 to 2012
$4.1M
Typhoid Pathogenesis and ImmunityR01AI112640 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2015 to 2019
$2.1M
Antimicrobial Actions of Nitric OxideR01AI118962 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2016 to 2020
$1.9M
Regulation of S. aureus Colonization by NO.R01AI123124 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2016 to 2020
$1.9M
DNA DAMAGE AND REPAIR IN SALMONELLA PATHOGENESISR01AI050660 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2003 to 2007
$1.9M
Silencing and Counter-Silencing of Salmonella Virulence GenesR01AI101084 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2012 to 2015
$1.5M
Iron Homeostasis in Salmonella-Host InteractionsR01AI077629 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2009 to 2010
$780k
Analysis of intracellular host defenses in Salmonella pathogenesisR56AI054959 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2008 to 2008
$378k
Citrate and Metal Efflux by IceTF32AI112101 · NIAID · UNIVERSITY OF WASHINGTON · PI FRAWLEY, ELAINE R. · 2014 to 2016
$135k
Molecular Analysis of Bacterial Adaptive Response to Host Reactive SpeciesI01BX002073 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Andres Vazquez-Torres · 2013 to 2026
–
BLRD VA I01 BX002073NIAID NIH HHS F32 AI112101NIAID NIH HHS R01 AI039557NIAID NIH HHS R01 AI044486NIAID NIH HHS R01 AI050660NIAID NIH HHS R01 AI054959NIAID NIH HHS R01 AI077629NIAID NIH HHS R01 AI101084NIAID NIH HHS R01 AI112640NIAID NIH HHS R01 AI118962NIAID NIH HHS R01 AI123124NIAID NIH HHS R56 AI054959
6 · The paper itself

Abstract

Pathogenic bacteria must withstand diverse host environments during infection. Environmental signals, such as pH, temperature, nutrient limitation, etc., not only trigger adaptive responses within bacteria to these specific stress conditions but also direct the expression of virulence genes at an appropriate time and place. An appreciation of stress responses and their regulation is therefore essential for an understanding of bacterial pathogenesis. This review considers specific stresses in the host environment and their relevance to pathogenesis, with a particular focus on the enteric pathogen Salmonella.

Indexed as

Adaptation, PhysiologicalHost-Pathogen InteractionsStress, PhysiologicalGene Expression Regulation, BacterialSalmonellaSalmonella InfectionsVirulence FactorsVirulence Factors

Identifiers

PMID27512901
PMCPMC4985009

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.