ReviewApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2016
"Weighing" the effects of exercise and intrinsic aerobic capacity: are there beneficial effects independent of changes in weight?
Review in Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes.Diabetes, obesity & metabolism · 2017Trial
- Kiss1-FASN participates fatty acid synthesis via high-fat diet in PgVAT of female mice.Journal of lipid research · 2026Article
- Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice.npj aging · 2022Article
- Ovulation induction techniques in women with polycystic ovary syndrome.Frontiers in medicine · 2022Review
- Obesity treatment: Weight loss versus increasing fitness and physical activity for reducing health risks.iScience · 2021Review
- Exercise induces favorable metabolic changes in white adipose tissue preventing high-fat diet obesity.Physiological reports · 2021Article
- Effects of metabolic state on the regulation of melanocortin circuits.Physiology & behavior · 2020Review
- Divergence in aerobic capacity impacts bile acid metabolism in young women.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD.Medicine and science in sports and exercise · 2020Article
- Looking on the "brite" side exercise-induced browning of white adipose tissue.Pflugers Archiv : European journal of physiology · 2019Review
- Cellular and synaptic reorganization of arcuate NPY/AgRP and POMC neurons after exercise.Molecular metabolism · 2018Article
- Exercise Induces White Adipose Tissue Browning Across the Weight Spectrum in Humans.Frontiers in physiology · 2018Article
- Acute and chronic changes in rat soleus muscle after high-fat high-sucrose diet.Physiological reports · 2017Article
- Habitual physical activity protects against lipopolysaccharide-induced inflammation in mouse adipose tissue.Adipocyte · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
It has been known for centuries that regularly performed exercise has beneficial effects on metabolic health. Owing to its central role in locomotion and the fact that it accounts for a large majority of whole-body glucose disposal and fatty acid oxidation, the effects of exercise on skeletal muscle has been a central focus in exercise physiology research. With this being said it is becoming increasingly well recognized that both adipose tissue and liver metabolism are robustly modified by exercise, especially in conditions of obesity and insulin resistance. One of the difficult questions to address is if the effects of exercise are direct or occur secondary to exercise-induced weight loss. The purpose of this review is to highlight recent work that has attempted to tease out the protective effects of exercise, or intrinsic aerobic capacity, against metabolic and inflammatory challenges as it relates to the treatment and prevention of obesity and insulin resistance. Recent studies reporting improvements in liver and adipose tissue insulin action following a single bout of exercise will also be discussed. The research highlighted in this review sheds new insight into protective, anti-inflammatory effects of exercise that occur largely independent of changes in adiposity and body weight.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.