ReviewObstetric medicine2015
Severe gestational hypertriglyceridemia: A practical approach for clinicians.
Review in Obstetric medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 79 citations in OpenAlex.
- A 35-Year-Old Woman With Recurrent Hypertriglyceridemia-Induced Pancreatitis in Pregnancy Managed With Fenofibrate and Plasmapheresis.The American journal of case reports · 2026Article
- Multidisciplinary Rescue for a Lethal Triad: Severe Hypertriglyceridemia, Necrotizing Pancreatitis, and Abdominal Compartment Syndrome in Pregnancy.Journal of lipid and atherosclerosis · 2026Article
- Gestational Hypertriglyceridemia Management and the Utility of Multidisciplinary Care.JACC. Case reports · 2026Article
- Course of Pregnancies and Occurrence of Acute Pancreatitis in Women With Chylomicronemia.The Journal of clinical endocrinology and metabolism · 2026Article
- Genetic Insights on Hypertriglyceridaemia-Induced Acute Pancreatitis in Pregnancy: A Case Series and Literature Review.Case reports in endocrinology · 2026Article
- Navigating hypertriglyceridemia in pregnancy: current evidence and clinical strategies.Frontiers in endocrinology · 2026Review
- Severe Hypertriglyceridemia in Pregnancy: Clinical Approach and Management Strategies.JCEM case reports · 2025Article
- Hypertriglyceridemia induced acute pancreatitis in pregnancy: a case report.Annals of medicine and surgery (2012) · 2025Article
- Plasmapheresis for Hypertriglyceridemia-induced Acute Pancreatitis: A Systematic Review and Meta-summary of Case Reports.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Review
- Extreme Pregnancy-Induced Hypertriglyceridemia Resulting in Pancreatitis: A Case Report.The American journal of case reports · 2025Article
- Management of Severe Hypertriglyceridemia in Pregnancy With Niacin: Reevaluating Safety and Therapeutic Benefits.Case reports in endocrinology · 2025Article
- Characteristics, Physiopathology and Management of Dyslipidemias in Pregnancy: A Narrative Review.Nutrients · 2024Review
- Obstetrical Management of Severe Hypertriglyceridemia in Pregnancy: A Case Report.AJP reports · 2024Article
- When pregnancy-associated hypertriglyceridemia goes above and beyond the risk of pancreatitis.Internal and emergency medicine · 2024Article
- Peripartum Lipid Apheresis: Novel Management of Familial Hyperlipidemia in Pregnancy.JACC. Case reports · 2023Article
- Assessment of the Risk of Future Metabolic Syndrome among Non-Hypertensive and Non-Diabetic Nigerian Pregnant Women Presenting with either Glycosuria or Proteinuria at Different Trimesters.Rwanda journal of medicine and health sciences · 2023Article
- Recurrent pancreatitis secondary to hypertriglyceridemia: A case report and case review.Clinical case reports · 2023Article
- Ecological change of the gut microbiota during pregnancy and progression to dyslipidemia.NPJ biofilms and microbiomes · 2023Article
- Brazilian Position Statement for Familial Chylomicronemia Syndrome - 2023.Arquivos brasileiros de cardiologia · 2023Article
- Lipid-Lowering Therapy in Women of Childbearing Age: a Review and Stepwise Clinical Approach.Current cardiology reports · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe gestational hypertriglyceridemia is a potentially life threatening and complex condition to manage, requiring attention to a delicate balance between maternal and fetal needs. During pregnancy, significant alterations to lipid homeostasis occur to ensure transfer of nutrients to the fetus. In women with an underlying genetic predisposition or a secondary exacerbating factor, severe gestational hypertriglyceridemia can arise, leading to devastating complications, including acute pancreatitis. Multidisciplinary care, implementation of a low-fat diet with nutritional support, and institution of a hierarchical therapeutic approach are all crucial to reduce maternal and fetal morbidity. To avoid maternal pancreatitis, close surveillance of triglycerides throughout pregnancy with elective hospitalization for refractory cases is recommended. Careful dietary planning is required to prevent neural and retinal complications from fetal essential fatty acid deficiency. Questions remain about the safety of fibrates and plasmapheresis in pregnancy as well as the optimal timing for induction and delivery of these women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.