Evidence map›Paper›PMID 27512022›Full record

ArticleJournal of neurophysiology2016

Nonreciprocal mechanisms in up- and downregulation of spinal motoneuron excitability by modulators of KCNQ/Kv7 channels.

Joseph Lombardo, Melissa A Harrington

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  3. Review
  4. Motor control: Snake neurons speed up.Current biology : CB · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joseph LombardoDepartment of Biological Sciences, Delaware State University, Dover, Delaware.
Melissa A HarringtonDepartment of Biological Sciences, Delaware State University, Dover, Delaware mharrington@desu.edu.
Delaware State University · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Anjana Narayan Bhat · 2012 to 2026
$67.2M
Updated confocal microscope in the Imaging Core facility to support biomedical researchP20GM103653 · NIGMS · DELAWARE STATE UNIVERSITY · PI HARRINGTON, MELISSA A · 2012 to 2022
$22.7M
A tale of two synapses: The development of neurotransmitter phenotype in motor neuronsR15HD075207 · NICHD · DELAWARE STATE UNIVERSITY · PI HARRINGTON, MELISSA A · 2013 to 2015
$551k
NICHD NIH HHS R15 HD075207NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P20 GM103653
6 · The paper itself

Abstract

KCNQ/K

Indexed as

Action PotentialsAnimalsAnimals, NewbornDown-RegulationExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsKCNQ Potassium ChannelsMiceMotor NeuronsOrgan Culture TechniquesSpinal CordUp-RegulationExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsKCNQ Potassium Channelsmembrane propertiesretigabinespinal cordvoltage thresholdXE991

Identifiers

PMID27512022
PMCPMC5102305
OpenAlexW2490212296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.