Evidence map›Paper›PMID 27511927›Full record

ArticleThe Journal of nutrition2016

Among 4 Diet Quality Indexes, Only the Alternate Mediterranean Diet Score Is Associated with Better Colorectal Cancer Survival and Only in African American Women in the Multiethnic Cohort.

Simone Jacobs, Brook E Harmon, Nicholas J Ollberding, Lynne R Wilkens, Kristine R Monroe, Laurence N Kolonel, Loic Le Marchand, Carol J Boushey, Gertraud Maskarinec

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 10 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 10 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Simone JacobsUniversity of Hawaii Cancer Center, Honolulu, HI;
Brook E HarmonSchool of Public Health, University of Memphis, Memphis, TN;
Nicholas J OllberdingCincinnati Children's Hospital Medical Center, Cincinnati, OH; and.
Lynne R WilkensUniversity of Hawaii Cancer Center, Honolulu, HI;
Kristine R MonroeUniversity of Southern California, Health Sciences Campus, Los Angeles, CA.
Laurence N KolonelUniversity of Hawaii Cancer Center, Honolulu, HI;
Loic Le MarchandUniversity of Hawaii Cancer Center, Honolulu, HI;
Carol J BousheyUniversity of Hawaii Cancer Center, Honolulu, HI;
Gertraud MaskarinecUniversity of Hawaii Cancer Center, Honolulu, HI; gertraud@cc.hawaii.edu.
University of Hawaiʻi at Mānoa · USCincinnati Children's Hospital Medical Center · USUniversity of Memphis · USUniversity of Southern California · US

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Xin Chen · 1996 to 2026
$56.2M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
WS No. 9 Health Eating Activity and Lifestyle StudyN01PC35139 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DEAPEN, DENNIS M. · 2007 to 2010
$8.6M
Nutritional & Behavioral Cancer Prevention in a Multiethnic PopulationR25CA090956 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI MASKARINEC, GERTRAUD · 2002 to 2012
$5.1M
WS No. 12 Patterns of Care DX Year 2008N01PC35137 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GOODMAN, MARC T · 2007 to 2009
$2.7M
NCI NIH HHS N01PC35137NCI NIH HHS N01PC35139NCI NIH HHS P30 CA071789NCI NIH HHS R25 CA090956NCI NIH HHS U01 CA164973
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) is the second leading cause of cancer-related death in the United States, with a 5-y survival rate of ∼65%. Therefore, the identification of modifiable health factors to improve CRC survival is crucial.

objectiveWe investigated the association of 4 prediagnostic a priori diet quality indexes with CRC-specific and all-cause mortality in the Multiethnic Cohort (MEC).

methodsThe MEC included >215,000 African-American, Native Hawaiian, Japanese-American, Latino, and white adults living in Hawaii and California who completed a validated quantitative food-frequency questionnaire in 1993-1996. CRC cases and deaths were identified through linkages to cancer registries and to state and national vital registries. Sex-specific HRs and 95% CIs were estimated for the Healthy Eating Index (HEI) 2010, the Alternative HEI (AHEI) 2010, the alternate Mediterranean Diet (aMED) score, and the Dietary Approaches to Stop Hypertension (DASH) index with CRC-specific and overall mortality as the primary outcomes. Ethnicity-specific analyses were the secondary outcomes.

resultsAmong 4204 MEC participants diagnosed with invasive CRC through 2010, 1976 all-cause and 1095 CRC-specific deaths were identified. A higher aMED score was associated with lower CRC-specific mortality in women [HR continuous pattern score divided by its respective SD (HR1SD): 0.86; 95% CI: 0.77, 0.96] but not in men (HR1SD: 1.01; 95% CI: 0.92, 1.11). A higher aMED score was also associated with lower all-cause mortality in women (HR1SD: 0.88; 95% CI: 0.81, 0.96) but not in men (HR1SD: 1.00; 95% CI: 0.93, 1.07). The HEI-2010, AHEI-2010, and DASH index were not significantly associated with CRC-specific or with all-cause mortality. The inverse relation for the aMED score was limited to African Americans and to colon (compared with rectal) cancer.

conclusionsThe aMED score was related to lower mortality only in African-American women (1 of 5 ethnic groups studied). The results should be interpreted with caution due to the small numbers of cases within ethnic groups and the issue of multiple testing.

Indexed as

DietDiet, MediterraneanMortalityAgedAsianBlack or African AmericanBody Mass IndexCaliforniaColorectal NeoplasmsExerciseFemaleFollow-Up StudiesHawaiiHispanic or LatinoHumansMalealternate Mediterranean Diet scoreAlternative Healthy Eating Indexcolorectal cancerCox regressionDietary Approaches to Stop Hypertension indexdietary patternsHealthy Eating IndexMultiethnic Cohortnutritionsurvival

Identifiers

PMID27511927
PMCPMC4997287
OpenAlexW2496515675

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.