ArticleJournal of clinical hypertension (Greenwich, Conn.)2017
Effects of Obesity and Hypertension on Pulse Wave Velocity in Children.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04735874 (Vascular Health and Risk Factors in Children With Down Syndrome), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vascular Health and Risk Factors in Children With Down Syndrome
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of blood pressure, obesity and physical activity with arterial stiffness in children: a systematic review and meta-analysis.Pediatric research · 2022Pooled it
- N-of-1 Trials vs. Usual Care in Children With Hypertension: A Pilot Randomized Clinical Trial.American journal of hypertension · 2023Trial
- Hypertension and vascular health in the young.Current opinion in pediatrics · 2025Review
- Are Advanced Glycation End-Products and Skin Autofluorescence Associated with E-Selectin and Pulse Wave Velocity as Markers of Atherosclerosis Risk in Children with Obesity?International journal of molecular sciences · 2025Article
- Markers of Vascular Function and Future Coronary Artery Disease Risk Among Malaysians with Individual Cardiovascular Risk Factors.Biomedicines · 2025Article
- Arterial stiffness as a screening tool for cardiovascular risk in health and disease.Journal of family medicine and primary care · 2024Article
- Pulse Wave Velocity: Methodology, Clinical Applications, and Interplay with Heart Rate Variability.Reviews in cardiovascular medicine · 2024Review
- Pulse Wave Analysis in Obese Children with and without Metabolic SyndromeJournal of clinical research in pediatric endocrinology · 2023Article
- Blood pressure parameters affecting ventricular repolarization in obese children.Pediatric nephrology (Berlin, Germany) · 2023Article
- Double-Trouble: Atherosclerotic Risk Factors and Congenital Heart Disease.Current atherosclerosis reports · 2023Review
- Article
- Is There a Role for Imaging Youth at Risk of Atherosclerosis?Current atherosclerosis reports · 2023Review
- Evaluating the Arterial Stiffness as a Useful Tool in the Management of Obese Children.Children (Basel, Switzerland) · 2023Article
- Relationship between the Dietary Inflammatory Index and Cardiovascular Health among Children.International journal of environmental research and public health · 2022Article
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Body Composition and Cardiovascular Risk Factors in a Paediatric Population.Children (Basel, Switzerland) · 2022Article
- The Role of Urate in Cardiovascular Risk in Adolescents and Young Adults With Hypertension, Assessed by Pulse Wave Velocity.Frontiers in cardiovascular medicine · 2022Article
- Does body mass index or waist-hip ratio correlate with arterial stiffness based on brachial-ankle pulse wave velocity in Chinese rural adults with hypertension?BMC cardiovascular disorders · 2021Article
- Ultrasonography to detect cardiovascular damage in children with essential hypertension.Cardiovascular ultrasound · 2021Article
- Could arterial stiffness be early reversible target organ damage test in childhood hypertension?Anatolian journal of cardiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Pulse wave velocity (PWV) is a biomarker of arterial stiffness. Findings from prior studies are conflicting regarding the impact of obesity on PWV in children. The authors measured carotid-femoral PWV in 159 children aged 4 to 18 years, of whom 95 were healthy, 25 were obese, 15 had hypertension (HTN), and 24 were both obese and hypertensive. Mean PWV increased with age but did not differ by race or sex. In adjusted analyses in children 10 years and older (n=102), PWV was significantly higher in children with hypertension (PWV±standard deviation, 4.9±0.7 m/s), obesity (5.0±0.9 m/s), and combined obesity-hypertension (5.2±0.6 m/s) vs healthy children (4.3±0.7 m/s) (each group, P<.001 vs control). In our study, obesity and HTN both significantly and independently increased PWV, while African American children did not have a higher PWV than Caucasian children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.