Evidence map›Paper›PMID 27511817›Full record

ReviewInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2016

Neurovascular manifestations of connective-tissue diseases: A review.

Sarasa T Kim, Waleed Brinjikji, Giuseppe Lanzino, David F Kallmes

Abstract readReview
In one paragraph

Review in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Treatment of pediatric intracranial aneurysms: institutional case series and systematic literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
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  9. Vertebral-Venous fistulas: Single center experience and practical treatment approach.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sarasa T KimMayo Clinic, Mayo Medical School, USA.
Waleed BrinjikjiMayo Clinic, Department of Radiology, USA brinjikji.waleed@mayo.edu.
Giuseppe LanzinoMayo Clinic, Department of Neurologic Surgery, USA.
David F KallmesMayo Clinic, Department of Radiology, USA.
Mayo Clinic in Arizona · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with connective tissue diseases are thought to be at a higher risk for a number of cerebrovascular diseases such as intracranial aneurysms, dissections, and acute ischemic strokes. In this report, we aim to understand the prevalence and occurrences of such neurovascular manifestations in four heritable connective tissue disorders: Marfan syndrome, Ehlers-Danlos syndrome, Neurofibromatosis Type 1, and Loeys-Dietz syndrome. We discuss the fact that although there are various case studies reporting neurovascular findings in these connective tissue diseases, there is a general lack of case-control and prospective studies investigating the true prevalence of these findings in these patient populations. Furthermore, the differences observed in the manifestations and histology of such disease pathologies encourages future multi-center registries and studies in better characterizing the pathophysiology, prevalence, and ideal treatment options of neurovascular lesions in patents with connective tissue diseases.

Indexed as

Connective Tissue DiseasesEhlers-Danlos SyndromeHumansIntracranial AneurysmLoeys-Dietz SyndromeMarfan SyndromeNervous System DiseasesVascular DiseasesdissectionEhlers–Danlos syndromeintracranial aneurysmLoeys–Dietz syndromeMarfan syndromeneurofibromatosis type 1 (NF1)

Identifiers

PMID27511817
PMCPMC5564353
OpenAlexW2505025059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.