Evidence map›Paper›PMID 27511601›Full record

ArticleMolecular medicine reports2016

Age‑dependent increase in the expression of antioxidant‑like protein‑1 in the gerbil hippocampus.

Jin-A Park, Joon Ha Park, Ji Hyeon Ahn, Jong-Dai Kim, Moo-Ho Won, Choong-Hyun Lee

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jin-A ParkDepartment of Pharmacy, College of Pharmacy, Dankook University, Cheonan, South Chungcheong 31116, Republic of Korea.
Joon Ha ParkDepartment of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Ji Hyeon AhnDepartment of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Jong-Dai KimDivision of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Moo-Ho WonDepartment of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Choong-Hyun LeeDepartment of Pharmacy, College of Pharmacy, Dankook University, Cheonan, South Chungcheong 31116, Republic of Korea.
Kangwon National University · KRDankook University · KRHallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidant-like protein-1 (AOP-1) reduces the intracellular level of reactive oxygen species. In the present study, the age‑related change in AOP‑1 expression in the hippocampus among young, adult and aged gerbils was compared using western blot analysis and immunohistochemistry. The results demonstrated that the protein expression of AOP‑1 was gradually and significantly increased in the hippocampus during the normal aging process. In addition, the age‑dependent increase in AOP‑1 immunoreactivity was also observed in pyramidal neurons of the hippocampus proper; however, in the dentate gyrus, AOP‑1 immunoreactivity was not altered during the normal aging process. These results indicated that the expression of AOP‑1 is significantly increased in the hippocampus proper, but not in the dentate gyrus, during the normal aging process.

Indexed as

AgingAnimalsDentate GyrusGerbillinaeHippocampusMalePeroxiredoxin IIIPeroxiredoxin III

Identifiers

PMID27511601
PMCPMC5042740
OpenAlexW2509708626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.