ReviewPhysiology (Bethesda, Md.)2016
Gut Microbiota: Modulation of Host Physiology in Obesity.
Review in Physiology (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Risk factors for enteral feeding intolerance in critically ill patients: an updated systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Association of gastrointestinal microbiome and obesity with gestational diabetes mellitus-an updated globally based review of the high-quality literatures.Nutrition & diabetes · 2024Pooled it
- The Effects of a Prebiotic Formula PromotingInternational journal of medical sciences · 2026Trial
- Lower Pretreatment Gut Integrity Is Independently Associated With Fat Gain on Antiretroviral Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Trial
- Gut Microbiome in Obesity: A Narrative Review of Mechanisms, Interventions, and Future Directions.Probiotics and antimicrobial proteins · 2026Review
- Exploring the relationship between APOEε4 allele and gut microbiota composition and function in healthy adults.AMB Express · 2025Article
- Regulatory Roles of Quercetin in Alleviating Fructose-Induced Hepatic Steatosis: Targeting Gut Microbiota and Inflammatory Metabolites.Food science & nutrition · 2025Article
- Causal effect of gut microbiota on the risk of prostatitis: a two-sample Mendelian randomization study.International urology and nephrology · 2024Article
- Improved Gut Health May Be a Potential Therapeutic Approach for Managing Prediabetes: A Literature Review.Biomedicines · 2024Review
- Understanding the Effect of Compound Probiotics on the Health of Rabbits and Its Mechanisms Through Metagenomics.Probiotics and antimicrobial proteins · 2024Article
- Average Daily Gain in Lambs Weaned at 60 Days of Age Is Correlated with Rumen and Rectum Microbiota.Microorganisms · 2023Article
- Probiotics therapy show significant improvement in obesity and neurobehavioral disorders symptoms.Frontiers in cellular and infection microbiology · 2023Review
- Collection of biospecimens from parent-child dyads in a community garden-based nutrition intervention: protocol and feasibility.BMC nutrition · 2022Article
- Therapeutic Antiaging Strategies.Biomedicines · 2022Review
- The standardisation of the approach to metagenomic human gut analysis: from sample collection to microbiome profiling.Scientific reports · 2022Article
- Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment.Frontiers in immunology · 2022Review
- Article
- Taxonomic Characterization and Short-Chain Fatty Acids Production of the Obese Microbiota.Frontiers in cellular and infection microbiology · 2021Article
- The First Report of Differences in Gut Microbiota Composition between Obese and Normal Weight Iranian SubjectsIranian biomedical journal · 2020Article
- Microbial Medicine: Prebiotic and Probiotic Functional Foods to Target Obesity and Metabolic Syndrome.International journal of molecular sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Many factors are involved in weight gain and metabolic disturbances associated with obesity. The gut microbiota has been of particular interest in recent years, since both human and animal studies have increased our understanding of the delicate symbiosis between the trillions of microbes that reside in the GI tract and the host. It has been suggested that disruption of this mutual tolerance may play a significant role in modulating host physiology during obesity. Environmental influences such as diet, exercise, and early life exposures can significantly impact the composition of the microbiota, and this dysbiosis can in turn lead to increased host adiposity via a number of different mechanisms. The ability of the microbiota to regulate host fat deposition, metabolism, and immune function makes it an attractive target for achieving sustained weight loss.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.