ReviewCurrent treatment options in neurology2016
Treatment of Inappropriate Sexual Behavior in Dementia.
Review in Current treatment options in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 81 citations in OpenAlex.
- The Off-Label Use of Selective Serotonin Reuptake Inhibitors for Sexual Behavior Management: Risks and Considerations.Healthcare (Basel, Switzerland) · 2025Review
- Impact of hypersexuality on spousal carers of patients with Parkinson's disease and frontotemporal dementia: a qualitative study.BMJ open · 2025Article
- From 'support' to 'separate': residential aged care staff responses to an intimate relationship involving a resident with cognitive impairment.BMC geriatrics · 2025Article
- The Law, Dementia, and Sexuality-Is the Law Striking the Right Balance?The Gerontologist · 2024Article
- Investigating the relevance of the advanced activities of daily living tool for the screening and diagnosis of mild cognitive impairment and dementia to the Sub-Saharan African migrant population in Belgium: A qualitative focus group study.The British journal of occupational therapy · 2024Article
- The Prevalence and Risk Factors of Sexual Dysfunction in the Elderly in Southern China.International journal of general medicine · 2024Article
- Pharmacologic management of inappropriate sexual behaviour in long-term care residents.Canadian family physician Medecin de famille canadien · 2023Article
- The impact of cognitive impairment in urologic implants: a narrative review.Translational andrology and urology · 2023Review
- Gender Differences in Disease, Function, and Behavioral Symptoms in Residents with Dementia.Western journal of nursing research · 2022Article
- Is Thalamic Lesion a Contributing Factor for Inappropriate Sexual Behavior in Older Adults with Cognitive Impairment?Journal of neurosciences in rural practice · 2022Article
- Rehabilitation in Dementia.Indian journal of psychological medicine · 2021Article
- The prevalence and determinants of inappropriate sexual behaviour in people with acquired brain injury in nursing homes.Journal of advanced nursing · 2021Observational
- Person-Centered Care Plans for Nursing Home Residents With Behavioral and Psychological Symptoms of Dementia.Journal of gerontological nursing · 2020Article
- Sexuality and the Older Adult.Current psychiatry reports · 2019Review
- Pharmacologic Management of Agitation in Patients with Dementia.Current geriatrics reports · 2019Article
- Reliability and Validity of the Care Plan Checklist for Evidence of Person-Centered Approaches for Behavioral and Psychological Symptoms Associated With Dementia.Journal of the American Medical Directors Association · 2018Article
- Aripiprazole for the Treatment of Inappropriate Sexual Behavior: Case Report of an Alzheimer's Disease Patient Known as Heterosexual with Recently Shifted Sexual Orientation to Same Gender.Journal of Alzheimer's disease reports · 2018Article
- The Impact of Inappropriate Sexual Behaviors in People With Dementia on Family Caregivers: A Scoping Review.American journal of Alzheimer's disease and other dementiasArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementInappropriate sexual behavior (ISB) is a relatively common and potentially disruptive form of behavior in people with dementia. It can cause considerable distress and put placements and people at risk. Yet it is poorly researched and understood. In addition to non-pharmacological approaches to management, a wide range of classes of medication has been used in ISB, and the results have been reported as single cases or short series, though none has been the subject of a randomized clinical trial, in part because of the lack of a well-defined method of observing and measuring ISB, as well as the significant ethical considerations. Pharmacological treatments for which there is low-level evidence of efficacy in the literature include antidepressants, antipsychotics, anticonvulsants, cholinesterase inhibitors, hormonal agents, and beta-blockers. None of the drugs discussed here is licensed for use in ISB, and elderly people, particularly those with dementia, are at high risk of adverse effects. Caution is advised before using medication in this group of people. It is important to consider alternative non-pharmacological treatments, as well as discussing issues of ethics and consent with those involved, before initiating treatment. It is helpful to identify and monitor target symptoms. Pharmacological treatments should be started at low dose and titrated up slowly and carefully. Nevertheless, in some situations, medication may provide a useful part of a management plan for ISB.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.