ArticleDigestive diseases and sciences2016
Prevalence and Predictors of Gastroesophageal Reflux Complications in Community Subjects.
Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Gastroesophageal disease risk and inhalational exposure a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Prevalence of Barrett's Esophagus and Esophageal Adenocarcinoma With and Without Gastroesophageal Reflux: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024Pooled it
- The global prevalence of Barrett's esophagus: A systematic review of the published literature.United European gastroenterology journal · 2020Pooled it
- Endoscopic Screening of Barrett's Esophagus.Gastrointestinal endoscopy clinics of North America · 2026Review
- Integrated network pharmacology and clinical study to reveal the efficacy and tolerability of Huoxue Tongjiang decoction for the treatment of non-erosive reflux disease-related symptoms.Journal of translational internal medicine · 2025Article
- Prevalence and Risk Factors of Gastroesophageal Reflux Disease in Patients with Dyspeptic and Reflux Symptoms: An Endoscopy-Based Prospective Study from Al Khobar, Saudi Arabia.Journal of epidemiology and global health · 2025Observational
- Study on the relationship of depression, anxiety, lifestyle and eating habits with the severity of reflux esophagitis.BMC gastroenterology · 2021Article
- Endoscopic Screening for Barrett's Esophagus and Esophageal Adenocarcinoma: Rationale, Candidates, and Challenges.Gastrointestinal endoscopy clinics of North America · 2021Review
- Recent Advances in Screening for Barrett's Esophagus.Current treatment options in gastroenterology · 2018Review
- Identification of key pathways and genes in Barrett's esophagus using integrated bioinformatics methods.Molecular medicine reports · 2018Article
- Dietary habits and obesity indices in patients with gastro-esophageal reflux disease: a comparative cross-sectional study.BMC gastroenterology · 2017Article
- Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature.Current gastroenterology reports · 2017Review
- Recent Advances in Non-invasive Esophageal Tissue Sampling.Current gastroenterology reports · 2017Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPredictors of erosive esophagitis (EE) and Barrett's esophagus (BE) and the influence of number of risk factors in the community are not well defined.
methodsRates of BE and EE among community residents identified in a randomized screening trial were defined. The risk of EE and BE associated with single and multiple risk factors (gender, age, GERD, Caucasian ethnicity, ever tobacco use, excess alcohol use, family history of BE or EAC, and central obesity) was analyzed.
resultsSixty-eight (33 %) of 205 subjects had EE and/or BE. BE prevalence was 7.8 % with dysplasia present in 1.5 %. Rates were comparable between subjects with and without GERD. Male sex and central obesity were independent risk factors. The odds of EE or BE were 3.7 times higher in subjects with three or four risk factors and 5.7 times higher in subjects with five or more risk factors compared with those with two or less factors.
conclusionsEE and BE are prevalent in the community regardless of the presence of GERD. Risk appeared to be additive, increasing substantially with three or more risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.