Evidence map›Paper›PMID 27510615›Full record

ArticleDrugs & aging2016

An Algorithm for Neuropathic Pain Management in Older People.

Gisèle Pickering, Margaux Marcoux, Sylvie Chapiro, Laurence David, Patrice Rat, Micheline Michel, Isabelle Bertrand, Marion Voute, Bernard Wary

Open access · hybridAbstract read
In one paragraph

Article in Drugs & aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Quality of Life Impact of an Adjuvanted Recombinant Zoster Vaccine in Adults Aged 50 Years and Older.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Trial
  4. Trial
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Neuropathic Pain in Nursing Homes.European journal of pain (London, England) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Gisèle PickeringCentre de Pharmacologie Clinique, Bâtiment 3C, CHU Clermont-Ferrand, 58 rue de Montalembert, 63001, Clermont-Ferrand Cedex, France. gisele.pickering@udamail.fr.
Margaux MarcouxCentre de Pharmacologie Clinique, Bâtiment 3C, CHU Clermont-Ferrand, 58 rue de Montalembert, 63001, Clermont-Ferrand Cedex, France.
Sylvie ChapiroPalliative Care, Hôpital Paul Brousse, 94800, Villejuif, France.
Laurence DavidCETD, Centre Hospitalier de la Côte Basque, 64100, Bayonne, France.
Patrice RatDepartment of Geriatrics, Marseille University Hospital, 13000, Marseille, France.
Micheline MichelDepartment of Geriatrics, Rennes University Hospital, 35000, Rennes, France.
Isabelle BertrandSanofi Pasteur MSD, 162 Avenue Jean Jaurès, 69367, Lyon Cedex 07, France.
Marion VouteCentre de Pharmacologie Clinique, Bâtiment 3C, CHU Clermont-Ferrand, 58 rue de Montalembert, 63001, Clermont-Ferrand Cedex, France.
Bernard WaryPalliative Care, Hôpital de Metz, France Service Régional De Soins Palliatifs, Hôpital Beauregard, CHR Metz-Thionville, 57126, Thionville, France.
Centre Hospitalier Universitaire de Clermont-Ferrand · FRCentre Hospitalier Régional de Metz-Thionville · FRCentre Hospitalier Universitaire de Rennes · FRHôpital Paul-Brousse · FRHospices Civils de Lyon · FRSanofi (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropathic pain frequently affects older people, who generally also have several comorbidities. Elderly patients are often poly-medicated, which increases the risk of drug-drug interactions. These patients, especially those with cognitive problems, may also have restricted communication skills, making pain evaluation difficult and pain treatment challenging. Clinicians and other healthcare providers need a decisional algorithm to optimize the recognition and management of neuropathic pain. We present a decisional algorithm developed by a multidisciplinary group of experts, which focuses on pain assessment and therapeutic options for the management of neuropathic pain, particularly in the elderly. The algorithm involves four main steps: (1) detection, (2) evaluation, (3) treatment, and (4) re-evaluation. The detection of neuropathic pain is an essential step in ensuring successful management. The extent of the impact of the neuropathic pain is then assessed, generally with self-report scales, except in patients with communication difficulties who can be assessed using behavioral scales. The management of neuropathic pain frequently requires combination treatments, and recommended treatments should be prescribed with caution in these elderly patients, taking into consideration their comorbidities and potential drug-drug interactions and adverse events. This algorithm can be used in the management of neuropathic pain in the elderly to ensure timely and adequate treatment by a multidisciplinary team.

Indexed as

AlgorithmsPractice Guidelines as TopicAgedComorbidityDrug InteractionsHumansNeuralgiaPain ManagementPain MeasurementSurveys and Questionnaires

Identifiers

PMID27510615
PMCPMC5012149
OpenAlexW2504732151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.