ArticleScientific reports2016
Retrieval-Based Model Accounts for Striking Profile of Episodic Memory and Generalization.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- The hippocampus rapidly integrates sequence representations during novel multistep predictions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Article
- Examining memory specificity and generalization contributions to false recall in DRM paradigm.Research square · 2026Article
- Affective schemas: Acquisition, updating, and inference.Emotion (Washington, D.C.) · 2026Article
- Episodic events are flexibly encoded in both integrated and separated neural representations.Nature communications · 2026Article
- Asymmetric learning and adaptability to changes in relational structure during transitive inference.Communications psychology · 2025Article
- The dependence of children's generalization on episodic memory varies with age and level of abstraction.Nature communications · 2025Article
- Reinforcement learning increasingly relates to memory specificity from childhood to adulthood.Nature communications · 2025Article
- The effects of episodic context on memory integration.Scientific reports · 2024Article
- Examining memory linking and generalization using scFLARE2, a temporally precise neuronal activity tagging system.Cell reports · 2023Article
- Mental representation of equivalence and order.Quarterly journal of experimental psychology (2006) · 2023Article
- Conceptual relatedness promotes memory generalization at the cost of detailed recollection.Scientific reports · 2023Article
- Generalization and false memory in acquired equivalence.Cognition · 2023Article
- Article
- Hippocampal and medial prefrontal cortices encode structural task representations following progressive and interleaved training schedules.PLoS computational biology · 2022Article
- Developmental differences in memory reactivation relate to encoding and inference in the human brain.Nature human behaviour · 2022Article
- Category-Biased Neural Representations Form Spontaneously during Learning That Emphasizes Memory for Specific Instances.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Stress-induced generalization of negative memories is mediated by an extended hippocampal circuit.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Contingency of semantic generalization on episodic specificity varies across development.Current biology : CB · 2021Article
- Healthy Middle-Aged Adults Have Preserved Mnemonic Discrimination and Integration, While Showing No Detectable Memory Benefits.Frontiers in psychology · 2021Article
- Generalization and False Memory in an Acquired Equivalence Paradigm: The Influence of Physical Resemblance Across Related Episodes.Frontiers in psychology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
A fundamental theoretical tension exists between the role of the hippocampus in generalizing across a set of related episodes, and in supporting memory for individual episodes. Whilst the former requires an appreciation of the commonalities across episodes, the latter emphasizes the representation of the specifics of individual experiences. We developed a novel version of the hippocampal-dependent paired associate inference (PAI) paradigm, which afforded us the unique opportunity to investigate the relationship between episodic memory and generalization in parallel. Across four experiments, we provide surprising evidence that the overlap between object pairs in the PAI paradigm results in a marked loss of episodic memory. Critically, however, we demonstrate that superior generalization ability was associated with stronger episodic memory. Through computational simulations we show that this striking profile of behavioral findings is best accounted for by a mechanism by which generalization occurs at the point of retrieval, through the recombination of related episodes on the fly. Taken together, our study offers new insights into the intricate relationship between episodic memory and generalization, and constrains theories of the mechanisms by which the hippocampus supports generalization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.