Trial reportSocial cognitive and affective neuroscience2016
Oxytocin enhances inter-brain synchrony during social coordination in male adults.
Trial report in Social cognitive and affective neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it, 183 citations in OpenAlex.
- Interpersonal neural synchrony and mental disorders: unlocking potential pathways for clinical interventions.Frontiers in neuroscience · 2024Pooled it
- Promoting Social Connectedness Through Interbrain Neurofeedback.Annals of the New York Academy of Sciences · 2025Trial
- Oxytocin increases physiological linkage during group therapy for methamphetamine use disorder: a randomized clinical trial.Scientific reports · 2021Trial
- Mortality threat mitigates interpersonal competition: an EEG-based hyperscanning study.Social cognitive and affective neuroscience · 2021Trial
- Oxytocin modulates the temporal dynamics of resting EEG networks.Scientific reports · 2019Trial
- Oxytocin enhances the pain-relieving effects of social support in romantic couples.Human brain mapping · 2019Trial
- Oxytocin effects on self-referential processing: behavioral and neuroimaging evidence.Social cognitive and affective neuroscience · 2017Trial
- Pupil-mimicry conditions trust in partners: moderation by oxytocin and group membership.Proceedings. Biological sciences · 2017Trial
- Heart rate synchrony as an objective biomarker in psychotherapy: a wearable-based pilot study.European archives of psychiatry and clinical neuroscience · 2026Article
- Endogenous oxytocin-linked heart-rate synchrony and social connection during live sports spectatorship.Translational psychiatry · 2026Article
- Neurophysiological mechanisms of embodied empathy in martial arts.Frontiers in psychology · 2026Article
- Correlation Between Electroencephalogram Brain-to-Brain Synchronization and Team Strategies and Tools to Enhance Performance and Patient Safety Scores During Online Hexad Virtual Simulation-Based Interprofessional Education: Cross-Sectional Correlational Study.JMIR medical education · 2025Article
- Dispositional empathy as a driver of inter-individual neural phase synchrony.Scientific reports · 2025Article
- How does oxytocin modulate human behavior?Molecular psychiatry · 2025Review
- Sensory multi-brain stimulation enhances dyadic cooperative behavior.Social cognitive and affective neuroscience · 2025Article
- Distinct fNIRS Inter-Brain Coupling Patterns for Cooperation versus Competition in a Tennis Game.Social cognitive and affective neuroscience · 2025Article
- Effects of oxytocin on agency in anxiously attached individuals: a replication and extension.Social cognitive and affective neuroscience · 2025Article
- Minding the moving self: the centrality of body movement in the neurodynamics of the self and psychotherapeutic implications.Frontiers in psychiatry · 2025Review
- How factors of the therapeutic alliance interact with oxytocin neurotransmission in psychotherapy.Frontiers in psychiatry · 2025Review
- A context-dependent model of resilient functioning after childhood maltreatment-the case for flexible biobehavioral synchrony.Translational psychiatry · 2024Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent brain imaging research has revealed oxytocin (OT) effects on an individual's brain activity during social interaction but tells little about whether and how OT modulates the coherence of inter-brain activity related to two individuals' coordination behavior. We developed a new real-time coordination game that required two individuals of a dyad to synchronize with a partner (coordination task) or with a computer (control task) by counting in mind rhythmically. Electroencephalography (EEG) was recorded simultaneously from a dyad to examine OT effects on inter-brain synchrony of neural activity during interpersonal coordination. Experiment 1 found that dyads showed smaller interpersonal time lags of counting and greater inter-brain synchrony of alpha-band neural oscillations during the coordination (vs control) task and these effects were reliably observed in female but not male dyads. Moreover, the increased alpha-band inter-brain synchrony predicted better interpersonal behavioral synchrony across all participants. Experiment 2, using a double blind, placebo-controlled between-subjects design, revealed that intranasal OT vs placebo administration in male dyads improved interpersonal behavioral synchrony in both the coordination and control tasks but specifically enhanced alpha-band inter-brain neural oscillations during the coordination task. Our findings provide first evidence that OT enhances inter-brain synchrony in male adults to facilitate social coordination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.