ArticleEnvironmental science and pollution research international2016
Antibiotic resistance, efflux pump genes and virulence determinants in Enterococcus spp. from surface water systems.
Article in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Prevalence of vancomycin-resistant enterococcus in Africa in one health approach: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Occurrence and Characterization of Antimicrobial-Resistant and VirulentAntibiotics (Basel, Switzerland) · 2026Article
- Tracking persistent and resistant Enterococcus faecalis and E. faecium from farm to fork: biofilm-linked risks in antibiotic resistance of isolates.Veterinary research communications · 2026Article
- Characterization of Enterococcus species in surface drinking water from Akoko Edo Nigeria reveals contamination levels and risks to public health.Scientific reports · 2025Article
- Phenotypic and genotypic characterization of antimicrobial resistance in Enterococcus spp. Isolated from the skin microbiota of channel catfish (Ictalurus punctatus) in Southeastern United States.BMC microbiology · 2025Article
- Virulence and Antibiotic Resistance Genes inMicroorganisms · 2025Article
- Occurrence of Trace-Level Antibiotics in the Msunduzi River: An Investigation into South African Environmental Pollution.Antibiotics (Basel, Switzerland) · 2024Article
- The phylogenomic landscape of extended-spectrum β-lactamase producing Citrobacter species isolated from surface water.BMC genomics · 2023Article
- Comparative Metagenomic and Metatranscriptomic Analyses Reveal the Response of Black Soldier Fly (Toxics · 2023Article
- Metal- and antibiotic-resistant heterotrophic plate count bacteria from a gold mine impacted river: the Mooi River system, South Africa.Environmental science and pollution research international · 2023Article
- Vancomycin Resistance inMicroorganisms · 2022Review
- Towards the standardization ofWater research X · 2022Review
- Antimicrobial Resistance Development Pathways in Surface Waters and Public Health Implications.Antibiotics (Basel, Switzerland) · 2022Review
- Draft Genome Sequences of Potentially Pathogenic Clostridium perfringens Strains from Environmental Surface Water in the North West Province of South Africa.Microbiology resource announcements · 2019Article
- Virulence profiles of vancomycin-resistant enterococci isolated from surface and ground water utilized by humans in the North West Province, South Africa: a public health perspective.Environmental science and pollution research international · 2019Article
- Detection of Virulence Genes in Multidrug Resistant Enterococci Isolated from Feedlots Dairy and Beef Cattle: Implications for Human Health and Food Safety.BioMed research international · 2019Article
- Mechanisms of Bacterial Tolerance and Persistence in the Gastrointestinal and Respiratory Environments.Clinical microbiology reviews · 2018Review
- Prevalence of virulence genes in Enterococcus species isolated from companion animals and livestock.The Onderstepoort journal of veterinary research · 2018Article
- Systematic review in South Africa reveals antibiotic resistance genes shared between clinical and environmental settings.Infection and drug resistance · 2018Review
- High Incidence of Virulence Factors Among Clinical Enterococcus faecalis Isolates in Southwestern Iran.Infection & chemotherapy · 2017Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to report on antibiotic susceptibility patterns as well as highlight the presence of efflux pump genes and virulence genetic determinants in Enterococcus spp. isolated from South African surface water systems. One hundred and twenty-four Enterococcus isolates consisting of seven species were identified. Antimicrobial susceptibility testing revealed a high percentage of isolates was resistant to β-lactams and vancomycin. Many were also resistant to other antibiotic groups. These isolates were screened by PCR, for the presence of four efflux pump genes (mefA, tetK, tetL and msrC). Efflux genes mefA and tetK were not detected in any of the Enterococcus spp. However, tetL and msrC were detected in 17 % of the Enterococcus spp. The presence of virulence factors in the Enterococcus spp. harbouring efflux pump genes was determined. Virulence determinants were detected in 86 % of the Enterococcus spp. harbouring efflux pump genes. Four (asa1, cylA, gel and hyl) of the five virulence factors were detected. The findings of this study have demonstrated that Enterococcus from South African surface water systems are resistant to multiple antibiotics, some of which are frequently used for therapy. Furthermore, these isolates harbour efflux pump genes coding for resistance to antibiotics and virulence factors which enhance their pathogenic potential.
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