Evidence map›Paper›PMID 27510035›Full record

ArticleThe Journal of biological chemistry2016

Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays.

Brandon Wadas, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Method Overview for Discovering ATE1 Substrates and their Arginylation Sites.Chembiochem : a European journal of chemical biology · 2025
    Review
  5. Article
  6. Assaying for Arginyltransferase Activity and Specificity by Peptide Arrays.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  7. Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. R-catcher, a potent molecular tool to unveil the arginylome.Cellular and molecular life sciences : CMLS · 2021
    Article
  10. Article
  11. Recognition of nonproline N-terminal residues by the Pro/N-degron pathway.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. Article
  13. Gid10 as an alternative N-recognin of the Pro/N-degron pathway.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Brandon WadasFrom the Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125.
Konstantin I Piatkovthe Center for Biotechnology and Biomedicine, Skolkovo Institute of Science and Technology, Moscow 143026, Russia, and.
Christopher S Browerthe Department of Biology, Texas Woman's University, Denton, Texas 76204.
Alexander VarshavskyFrom the Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, avarsh@caltech.edu.
California Institute of Technology · USSkolkovo Institute of Science and Technology · RUTexas Woman's University · US

Funding

The Functions, Mechanisms, and Regulation of N-Terminal ArginylationR01GM031530 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ALEXANDER J VARSHAVSKY · 1985 to 2026
$14.5M
Ubiquitin Ligases, Mechanisms and Functions of the N-End Rule PathwayR01DK039520 · NIDDK · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI VARSHAVSKY, ALEXANDER J · 1988 to 2025
$10.0M
NIDDK NIH HHS R01 DK039520NIGMS NIH HHS R01 GM031530
6 · The paper itself

Abstract

N

Indexed as

Protein Processing, Post-TranslationalAminoacyltransferasesAnimalsIsoenzymesMiceProtein Array AnalysisSubstrate SpecificityAminoacyltransferasesarginyltransferaseIsoenzymesarginyltransferaseAte1N-end ruleproteasomeprotein degradationubiquitinubiquitin ligaseubiquitylation (ubiquitination)

Identifiers

PMID27510035
PMCPMC5076509
OpenAlexW2492378617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.