Evidence map›Paper›PMID 27509449›Full record

ArticleOrganic letters2016

Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes.

YoungKu Kang, Daniel Seidel

Open access · greenAbstract read
In one paragraph

Article in Organic letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

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  9. The synthesis of imidazo[1,5-RSC advances · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

YoungKu KangDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey , Piscataway, New Jersey 08854, United States.
Daniel SeidelDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey , Piscataway, New Jersey 08854, United States.
Rutgers, The State University of New Jersey · US

Funding

Development of Strategies for the Functionalization of AminesR01GM101389 · NIGMS · UNIVERSITY OF FLORIDA · PI SEIDEL, DANIEL · 2012 to 2021
$2.5M
NIGMS NIH HHS R01 GM101389
6 · The paper itself

Abstract

Indolizidine and quinolizidine derivatives are readily assembled from proline or pipecolic acid and γ-nitroaldehydes by means of a decarboxylative annulation process. These reactions are promoted by simple acetic acid and involve azomethine ylides as reactive intermediates. The method was applied to the synthesis of an epiquinamide analog.

Indexed as

AldehydesAmino AcidsDecarboxylationMolecular StructureNitro CompoundsQuinolizinesAldehydesAmino AcidsepiquinamideNitro CompoundsQuinolizines

Identifiers

PMID27509449
PMCPMC5013532
OpenAlexW4241951775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.