ArticleRevista latino-americana de enfermagem2016
Diagnosis and medical treatment of neuropathic pain in leprosy.
Article in Revista latino-americana de enfermagem, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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4 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Disability as a neglected outcome of neglected tropical diseases: A systematic review.PLoS neglected tropical diseases · 2026Pooled it
- The Neurological Impact of Leprosy: Manifestations and Treatment Approaches.Neurology international · 2024Review
- Clinical prediction rules for the diagnosis of neuritis in leprosy.BMC infectious diseases · 2021Article
- Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy.PLoS neglected tropical diseases · 2018Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveto identify the difficulties in diagnosing and treating neuropathic pain caused by leprosy and to understand the main characteristics of this situation.
methods85 patients were treated in outpatient units with reference to leprosy and the accompanying pain. We used a questionnaire known as the Douleur Neuropathic 4 test and we conducted detailed neurological exams. As a result, 42 patients were excluded from the study for not having proved their pain.
resultsOut of the 37 patients that experienced pain, 22 (59.5%) had neuropathic pain (or a mixture of this pain and their existing pain) and of these 90.8% considered this pain to be moderate or severe. 81.8% of the sample suffered with this pain for more than 6 months. Only 12 (54.5%) of the patients had been diagnosed with neuropathic pain and in almost half of these cases, this pain had not been diagnosed. With reference to medical treatment (n=12) for neuropathic pain, 5 (41.6%) responded that they became better. For the other 7 (58.4%) there were no changes in relation to the pain or in some cases the pain worsened in comparison to their previous state. Statistical analysis comparing improvements in relation to the pain amongst the patients that were treated (n=12) and those that were not, showed significant differences (value p=0.020).
conclusionwe noted difficulties in diagnosing neuropathic pain for leprosy in that almost half of the patients that were studied had not had their pain diagnosed. We attributed this to some factors such as the non-adoption of the appropriate protocols which led to inadequate diagnosis and treatment that overlooked the true picture.
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