Evidence map›Paper›PMID 27508205›Full record

ArticleFrontiers in pediatrics2016

Comparing Outcomes of Two Types of Bariatric Surgery in an Adolescent Obese Population: Roux-en-Y Gastric Bypass vs. Sleeve Gastrectomy.

Giovana D Maffazioli, Fatima Cody Stanford, Karen J Campoverde Reyes, Takara L Stanley, Vibha Singhal, Kathleen E Corey, Janey S Pratt, Miriam A Bredella, Madhusmita Misra

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. ASMBS pediatric metabolic and bariatric surgery guidelines, 2018.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2018
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giovana D MaffazioliNeuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA.
Fatima Cody StanfordPediatric Endocrine Unit, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, USA; Weight Center, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine-Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Karen J Campoverde ReyesNeuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA.
Takara L StanleyNeuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Pediatric Endocrine Unit, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, USA.
Vibha SinghalNeuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Pediatric Endocrine Unit, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, USA.
Kathleen E CoreyDepartment of Medicine-Gastroenterology, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA.
Janey S PrattWeight Center, Massachusetts General Hospital, Boston, MA, USA; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Miriam A BredellaDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA.
Madhusmita MisraNeuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Pediatric Endocrine Unit, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, USA.
Massachusetts General Hospital · USHarvard University · US

Funding

Bone Metabolism and Body Composition in Young AthletesK24HD071843 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI MISRA, MADHUSMITA · 2013 to 2017
$930k
NICHD NIH HHS K24 HD071843
6 · The paper itself

Abstract

backgroundObesity is prevalent among adolescents and is associated with serious health consequences. Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) are bariatric procedures that cause significant weight loss in adults and are increasingly being performed in adolescents with morbid obesity. Data comparing outcomes of RYGB vs. SG in this age-group are scarce. This study aims to compare short-term (1-6 months) and longer-term (7-18 months) body mass index (BMI) and biochemical outcomes following RYGB and SG in adolescents/young adults.

methodsA retrospective study using data extracted from medical records of patients 16-21 years who underwent RYGB or SG between 2012 and 2014 at a tertiary care academic medical center.

resultsForty-six patients were included in this study: 24 underwent RYGB and 22 underwent SG. Groups did not differ for baseline age, sex, race, or BMI. BMI reductions were significant at 1-6 months and 7-18 months within groups (p < 0.0001), but did not differ by surgery type (p = 0.65 and 0.09, for 1-6 months and 7-18 months, respectively). Over 7-18 months, within-group improvement in low-density lipoprotein (LDL) (-24 ± 6 in RYGB, p = 0.003, vs. -7 ± 9 mg/dl in SG, p = 0.50) and non-high-density lipoprotein (non-HDL) cholesterol (-23 ± 8 in RYGB, p = 0.02, vs. -12 ± 7 in SG, p = 0.18) appeared to be of greater magnitude following RYGB. However, differences between groups did not reach statistical significance. When divided by non-alcoholic steatohepatitis stages (NASH), patients with Stage II-III NASH had greater reductions in alanine aminotransferase levels vs. those with Stage 0-I NASH (-45 ± 18 vs. -9 ± 3, p = 0.01) after 7-18 months. RYGB and SG groups did not differ for the magnitude of post-surgical changes in liver enzymes.

conclusionRYGB and SG did not differ for the magnitude of BMI reduction across groups, though changes trended higher following RYGB. Further prospective studies are needed to confirm these findings.

Indexed as

adolescencebariatric surgeryobesityRoux-en-Y gastric bypasssleeve gastrectomy

Identifiers

PMID27508205
PMCPMC4960456
OpenAlexW2491143783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.