Evidence map›Paper›PMID 27507993›Full record

ArticleJournal of dentistry (Tehran, Iran)2015

Regenerative Effects of Three Types of Allografts on Rabbit Calvarium: An Animal Study.

Amir Reza Rokn, Abbas Seyed Shakeri, Shahroo Etemad-Moghadam, Mojgan Alaeddini, Ahmad Reza Shamshiri, Rebecca Manasheof, Hamidreza Barikani

Abstract read
In one paragraph

Article in Journal of dentistry (Tehran, Iran), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Comparing the effects of BoneClinical and experimental dental research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amir Reza RoknProfessor, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Abbas Seyed ShakeriDental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Shahroo Etemad-MoghadamAssociate Professor, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mojgan AlaeddiniAssociate Professor, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Ahmad Reza ShamshiriStatistics Advisor, Dental School, Tehran University of Medical Sciences, Tehran, Iran.
Rebecca ManasheofDental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Hamidreza BarikaniDental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to histologically compare the regenerative properties of two allografts manufactured by two Iranian companies. MATERIALS AND

methodsIn this study, four 8-mm defects were produced in the calvaria of 12 rabbits. In three defects, three types of allografts namely ITB, CenoBone and Grafton were placed and one defect served as control. Samples were prepared and histomorphometric evaluations were carried out after healing periods of four weeks (interval 1) and eight weeks (interval 2). Qualitative and quantities variables were compared and analyzed with SPSS software.

resultsMild inflammation was observed in 45% and 12.5% of the samples in the first and second intervals, respectively. Foreign body reaction was observed in only 5% of the samples. The quality of regenerated bone was immature, mixed and lamellar in 54.5%, 15.9% and 4.5% of the samples, respectively. The rate of allograft resorption was the highest and lowest in the CenoBone and Grafton samples, respectively. The mean amount of regenerated bone was higher in areas containing Grafton; however, the differences were not statistically significant.

conclusionDespite the differences in the numerical values of bone regeneration, there were no statistically significant differences in bone generation among the material groups, and allografts manufactured in Iran can be suitable alternatives to Grafton with the same good properties. Further studies are necessary to clarify the efficacy of these allografts.

Indexed as

AllograftsBone RegenerationOsteogenesisRabbitsSkull

Identifiers

PMID27507993
PMCPMC4977406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.