Evidence map›Paper›PMID 27507572›Full record

ArticleAddiction biology2017

A dose-response estimate for acute alcohol use and risk of suicide attempt.

Guilherme Borges, Cheryl J Cherpitel, Ricardo Orozco, Yu Ye, Maristela Monteiro, Wei Hao, Vikram Benegal

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Addiction biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Modeling the reciprocal dynamic between alcohol and suicide urges among college students: Ecological momentary assessment study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026
    Article
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  8. Acute Alcohol Use and Suicide.JAMA network open · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Guilherme BorgesNational Institute of Psychiatry Ramon de la Fuente, Mexico City, Mexico.
Cheryl J CherpitelAlcohol Research Group, Emeryville, CA, USA.
Ricardo OrozcoNational Institute of Psychiatry Ramon de la Fuente, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-6580-585X
Yu YeAlcohol Research Group, Emeryville, CA, USA.
Maristela MonteiroPan American Health Organization (PAHO), Washington, DC, USA.
Wei HaoCentral South University, Hunan, China.
Vikram BenegalNational Institute of Mental Health and Neurosciences, Bangalore, India.
Alcohol Research Group · USInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXCentral South University · CNNational Institute of Mental Health and Neurosciences · INWorld Health Organization Regional Office for the Americas · US

Funding

Cross-National Analysis of Alcohol & InjuryR01AA013750 · NIAAA · PUBLIC HEALTH INSTITUTE · PI CHERPITEL, CHERYL J · 2002 to 2018
$4.4M
NIAAA NIH HHS R01 AA013750
6 · The paper itself

Abstract

This study reports dose-response estimates for the relative risk and population attributable risk (PAR) between acute alcohol use and serious suicide attempt. Data were analyzed on 272 suicide attempters arriving at 38 emergency departments within 6 hours of the event in 17 countries. Case-crossover analysis, pair-matching the number of standard drinks consumed within the 6 hours prior to the suicide attempt with that consumed during the same 6-hour period of the previous week, was performed using fractional polynomial analysis for dose-response. Every drink increased the risk of a suicide attempt by 30 percent; even one-two drinks was associated with a sizable increase in the risk of a serious suicide attempt, and a dose-response was found for the relationship between drinking 6 hours prior and the risk of a suicide attempt up to 20 drinks. Acute use of alcohol was responsible for 35 percent PAR of all suicide attempts. While very high levels of drinking were associated with larger relative risk s of suicide attempt, the control and reduction of smaller quantities of acute alcohol use also had an impact on population levels of suicide attempt, as showed here for the first time with our PAR estimates. Interventions to stop drinking or at least decrease levels of consumption could reduce the risk of suicide attempt. Screening people more at risk to suffer these acute effects of ethanol and offering interventions that work to these high-risk groups are a matter of urgent new research in the area.

Indexed as

AdultAlcohol DrinkingAlcohol-Related DisordersCross-Over StudiesDose-Response Relationship, DrugFemaleHumansInternationalityMaleRisk FactorsSuicide, Attemptedalcoholcase-crossoveremergency departmentrisksuicide attempt

Identifiers

PMID27507572
PMCPMC5303186
OpenAlexW2508682505

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.