Evidence map›Paper›PMID 27507259›Full record

ArticleRheumatology international2016

Anti-CCP status determines the power Doppler oscillation pattern in rheumatoid arthritis: a prospective study.

Ottar Gadeholt, Tobias Wech, Sebastian Schuh, Eva Scharbatke, Eva Ostermeier, Hans-Peter Tony, Marc Schmalzing

Abstract read
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In one paragraph

Article in Rheumatology international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ottar GadeholtDepartment of Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany. Gadeholt_o@ukw.de.ORCID http://orcid.org/0000-0001-6320-4818
Tobias WechDepartment of Experimental Radiology, University Clinic Wuerzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Sebastian SchuhDepartment of Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
Eva ScharbatkeDepartment of Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
Eva OstermeierDepartment of Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
Hans-Peter TonyDepartment of Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
Marc SchmalzingDepartment of Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
Universitätsklinikum Würzburg · DEUniversitäts-Kinderklinik Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction. Serologically, it can be differentiated according to rheumatoid factor (RF), anti-cyclic citrullinated peptide antibodies (anti-CCP), or both. This differentiation is prognostically and therapeutically relevant. No method has been described to separate the two forms phenotypically. We hypothesize that a differentiation is possible by evaluating oscillation patterns in power Doppler sonography (PDS). In a prospective study, 20 patients with anti-CCP-positive RA and 20 patients with anti-CCP-negative RA with active wrist synovitis were examined. A PDS scan was performed, and perfusion maxima (P

Indexed as

Ultrasonography, DopplerAdultAgedAged, 80 and overArthritis, RheumatoidAutoantibodiesFemaleHumansMaleMiddle AgedPeptides, CyclicProspective StudiesAutoantibodiescyclic citrullinated peptidePeptides, CyclicAnti-CCPPower Doppler sonographyRheumatoid arthritisRheumatoid factorUltrasonography

Identifiers

PMID27507259
OpenAlexW2508743938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.