ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Prognostic value of one millisievert exercise myocardial perfusion imaging in patients without known coronary artery disease.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- [Coronary heart disease-a German paradox : Using AI-based technology to solve a relevant healthcare problem].Herzschrittmachertherapie & Elektrophysiologie · 2026Review
- Reduced acquisition time for thallium myocardial perfusion imaging with large field cadmium-zinc-telluride SPECT/CT cameras: An equivalence study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Feasibility of simultaneous dual isotope acquisition for myocardial perfusion imaging with a cadmium zinc telluride camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Drivers of radiation dose reduction with myocardial perfusion imaging: A large health system experience.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Ultra-low-dose computed tomography for attenuation correction of cadmium-zinc-telluride single photon emission computed tomography myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- EANM procedural guidelines for myocardial perfusion scintigraphy using cardiac-centered gamma cameras.European journal of hybrid imaging · 2019Article
- The time is now: Dose reduction for myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to assess the prognostic value of normal ultra-low-dose exercise MPI with a CZT camera.
methods1901 consecutive patients without known CAD referred for exercise MPI with 1.8 MBq/kg (0.05 mCi) of Tc99m sestamibi or tetrofosmin and a CZT camera were included prospectively. Patients with an abnormal scan requiring an additional resting image (230) or a submaximal exercise test (271) were excluded. The 1400 remaining patients were followed for 39 months. The primary end-point was cardiac events (cardiac death, nonfatal myocardial infarction, and revascularization). The secondary end-point was noncardiac death.
resultsThe mean injected activity was 145 ± 37 MBq (3.9 ± 1 mCi), the mean acquisition duration was 10 ± 0.7 minutes, and the mean effective dose was 0.91 ± 0.13 mSv. 1288 patients (92%) achieved full follow-up. We observed 22 cardiac events and 16 noncardiac deaths. The annualized rates were equivalent to 0.55% for cardiac events and 0.37% for noncardiac mortality.
conclusionsNormal ultra-low-dose exercise MPI with a CZT camera has a high negative predictive value. The effective dose was less than 1 mSv, and the study thus allays concerns about radiation burden.
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