Evidence map›Paper›PMID 27506694›Full record

ArticleThe Journal of urology2017

Emotional Distress Increases the Likelihood of Undergoing Surgery among Men with Localized Prostate Cancer.

Heather Orom, Willie Underwood, Caitlin Biddle

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Heather OromUniversity at Buffalo (CB), Buffalo, New York; Roswell Park Cancer Institute, Buffalo, New York. Electronic address: horom@buffalo.edu.
Willie UnderwoodUniversity at Buffalo (CB), Buffalo, New York; Roswell Park Cancer Institute, Buffalo, New York.
Caitlin BiddleUniversity at Buffalo (CB), Buffalo, New York; Roswell Park Cancer Institute, Buffalo, New York.
Roswell Park Comprehensive Cancer Center · USUniversity at Buffalo, State University of New York · US

Funding

Race, Prostate Cancer Treatment, and Treatment Decision Difficulty and RegretR01CA152425 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI OROM, HEATHER, UNDERWOOD, WILLIE · 2010 to 2014
$2.8M
NCI NIH HHS R01 CA152425
6 · The paper itself

Abstract

purposeWe determined whether among men with clinically localized prostate cancer, particularly men with low risk disease, greater emotional distress increases the likelihood of undergoing surgery vs radiation or active surveillance. MATERIALS AND

methodsParticipants were 1,531 patients recruited from 2 academic and 3 community facilities (nonHispanic white 83%, nonHispanic black 11% and Hispanic 6%; low risk 36%, intermediate risk 49% and high risk 15%; choice of active surveillance 24%, radiation 27% and surgery 48%). Emotional distress was assessed shortly after diagnosis and after men made a treatment decision with the Distress Thermometer. We used multinomial logistic regression with robust standard errors to test if emotional distress at either point predicted treatment choice in the sample as a whole and after stratifying by D'Amico risk score.

resultsIn the sample as a whole the participants who were more emotionally distressed at diagnosis were more likely to choose surgery over active surveillance (RRR 1.07; 95% CI 1.01, 1.14; p=0.02). Men who were more distressed close to the time they made a treatment choice were more likely to have chosen surgery over active surveillance (RRR 1.16; 95% CI 1.09, 1.24; p <0.001) or surgery over radiation (RRR 1.12; 95% CI 1.05, 1.19; p=0.001). This pattern was also found in men with low risk disease.

conclusionsEmotional distress may motivate men with low risk prostate cancer to choose more aggressive treatment. Addressing emotional distress before and during treatment decision making may reduce a barrier to the uptake of active surveillance.

Indexed as

Decision MakingHumansMaleProstatic NeoplasmsStress, PsychologicalUrologic Surgical Procedures, MaleVisual Analog ScaleWatchful Waitingclinical decision-makingprostatic neoplasmspsychologicalstresswatchful waiting

Identifiers

PMID27506694
PMCPMC5241229
OpenAlexW2515083937

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.