Evidence map›Paper›PMID 27506579›Full record

ArticleAmerican journal of surgery2016

Variation in primary site resection practices for advanced colon cancer: a study using the National Cancer Data Base.

Mark A Healy, Jason C Pradarelli, Robert W Krell, Scott E Regenbogen, Pasithorn A Suwanabol

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mark A HealyDepartment of Surgery, University of Michigan Health System, Center for Healthcare Outcomes and Policy, 2800 Plymouth Road, Building 16, 016-100N28, Ann Arbor, MI 48109, USA. Electronic address: healym@umich.edu.
Jason C PradarelliUniversity of Michigan Medical School, Ann Arbor, MI, USA.
Robert W KrellDepartment of Surgery, University of Michigan Health System, Center for Healthcare Outcomes and Policy, 2800 Plymouth Road, Building 16, 016-100N28, Ann Arbor, MI 48109, USA.
Scott E RegenbogenDepartment of Surgery, University of Michigan Health System, Center for Healthcare Outcomes and Policy, 2800 Plymouth Road, Building 16, 016-100N28, Ann Arbor, MI 48109, USA.
Pasithorn A SuwanabolDepartment of Surgery, University of Michigan Health System, Center for Healthcare Outcomes and Policy, 2800 Plymouth Road, Building 16, 016-100N28, Ann Arbor, MI 48109, USA.

Funding

University of Michigan Surgical Oncology Research Training ProgramT32CA009672 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JACQUELINE SARA JERUSS, WEIPING ZOU · 1991 to 2026
$6.0M
NCI NIH HHS T32 CA009672
6 · The paper itself

Abstract

backgroundTreatment of metastatic colon cancer may be driven as much by practice patterns as by features of disease. To optimize management, there is a need to better understand what is determining primary site resection use.

methodsWe evaluated all patients with stage IV cancers in the National Cancer Data Base from 2002 to 2012 (50,791 patients, 1,230 hospitals). We first identified patient characteristics associated with primary tumor resection. Then, we assessed nationwide variation in hospital resection rates.

resultsOverall, 27,387 (53.9%) patients underwent primary site resection. Factors associated with resection included younger age, having less than 2 major comorbidities, and white race (P < .001). Nationwide, hospital-adjusted primary tumor resection rates ranged from 26.0% to 87.8% with broad differences across geographical areas and hospital accreditation types.

conclusionsThere is statistically significant variation in hospital rates of primary site resection. This demonstrates inconsistent adherence to guidelines in the presence of conflicting evidence regarding resection benefit.

Indexed as

AdultAgedAged, 80 and overAge FactorsChemotherapy, AdjuvantClinical Decision-MakingColonic NeoplasmsComorbidityDatabases, FactualFemaleHospitalsHumansMaleMiddle AgedMultivariate AnalysisPractice Patterns, Physicians'Clinical decision makingColon neoplasmsColon surgeryHospitalsNeoplasm metastasis

Identifiers

PMID27506579
PMCPMC5055429

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.