ArticleBMC genomics2016
The genome of the emerging barley pathogen Ramularia collo-cygni.
Article in BMC genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
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- Fungal Endophytes: Discovering What Lies within Some of Canada's Oldest and Most Resilient Grapevines.Journal of fungi (Basel, Switzerland) · 2024Article
- Pan-genome survey ofFrontiers in microbiology · 2024Article
- Functional genomics identifies a small secreted protein that plays a role during the biotrophic to necrotrophic shift in the root rot pathogenFrontiers in plant science · 2024Article
- Integrative transcript to proteome analysis of barley duringFrontiers in plant science · 2024Article
- Biosynthesis of Rubellins inInternational journal of molecular sciences · 2022Article
- The NativeFrontiers in microbiology · 2022Article
- Increased abundance of secreted hydrolytic enzymes and secondary metabolite gene clusters define the genomes of latent plant pathogens in the Botryosphaeriaceae.BMC genomics · 2021Article
- Fungicide Resistance Evolving inMicroorganisms · 2021Article
- Deciphering Molecular Host-Pathogen Interactions DuringFrontiers in plant science · 2021Article
- Proteinaceous effector discovery and characterization in filamentous plant pathogens.Molecular plant pathology · 2020Review
- Selected Fungal Natural Products with Antimicrobial Properties.Molecules (Basel, Switzerland) · 2020Review
- A New Reference Genome Shows the One-Speed Genome Structure of the Barley Pathogen Ramularia collo-cygni.Genome biology and evolution · 2018Article
- The role of reactive oxygen in the development of Ramularia leaf spot disease in barley seedlings.Annals of botany · 2018Article
- Transposable Element Genomic Fissuring inFrontiers in genetics · 2018Article
- The genome sequence of Bipolaris cookei reveals mechanisms of pathogenesis underlying target leaf spot of sorghum.Scientific reports · 2017Article
- Host-Multi-Pathogen Warfare: Pathogen Interactions in Co-infected Plants.Frontiers in plant science · 2017Review
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Authors and funding
17 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundRamularia collo-cygni is a newly important, foliar fungal pathogen of barley that causes the disease Ramularia leaf spot. The fungus exhibits a prolonged endophytic growth stage before switching life habit to become an aggressive, necrotrophic pathogen that causes significant losses to green leaf area and hence grain yield and quality.
resultsThe R. collo-cygni genome was sequenced using a combination of Illumina and Roche 454 technologies. The draft assembly of 30.3 Mb contained 11,617 predicted gene models. Our phylogenomic analysis confirmed the classification of this ascomycete fungus within the family Mycosphaerellaceae, order Capnodiales of the class Dothideomycetes. A predicted secretome comprising 1053 proteins included redox-related enzymes and carbohydrate-modifying enzymes and proteases. The relative paucity of plant cell wall degrading enzyme genes may be associated with the stealth pathogenesis characteristic of plant pathogens from the Mycosphaerellaceae. A large number of genes associated with secondary metabolite production, including homologs of toxin biosynthesis genes found in other Dothideomycete plant pathogens, were identified.
conclusionsThe genome sequence of R. collo-cygni provides a framework for understanding the genetic basis of pathogenesis in this important emerging pathogen. The reduced complement of carbohydrate-degrading enzyme genes is likely to reflect a strategy to avoid detection by host defences during its prolonged asymptomatic growth. Of particular interest will be the analysis of R. collo-cygni gene expression during interactions with the host barley, to understand what triggers this fungus to switch from being a benign endophyte to an aggressive necrotroph.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.