ReviewNeuroscience and biobehavioral reviews2016
The neurobiology of the emotional adolescent: From the inside out.
Review in Neuroscience and biobehavioral reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
136 citing papers in PubMed, 5 syntheses or guidelines pooled it, 299 citations in OpenAlex.
- The brain in social context: A systematic review of substance use and social processing from adolescence to young adulthood.Developmental cognitive neuroscience · 2022Pooled it
- The Transdiagnostic Origins of Anxiety and Depression During the Pediatric Period: Linking NIMH Research Domain Criteria (RDoC) Constructs to Ecological Systems.Development and psychopathology · 2021Pooled it
- Effectiveness of Virtual Reality Interventions for Adolescent Patients in Hospital Settings: Systematic Review.Journal of medical Internet research · 2021Pooled it
- Meta-analytic evidence for a joint neural mechanism underlying response inhibition and state anger.Human brain mapping · 2020Pooled it
- Brain and Cognitive Development in Adolescents with Anorexia Nervosa: A Systematic Review of fMRI Studies.Nutrients · 2019Pooled it
- The effects of physical activity on mental health in adolescents with attention-deficit hyperactivity disorder: a randomized controlled trial.The international journal of behavioral nutrition and physical activity · 2025Trial
- Autonomic reactivity to social rejection, peer difficulties, and the buffering effects of adolescent friendships following early psychosocial deprivation.Emotion (Washington, D.C.) · 2022Trial
- Applying new RDoC dimensions to the development of emotion regulation: Examining the influence of maternal emotion regulation on within-individual change in child emotion regulation.Development and psychopathology · 2021Trial
- The prospective association between stressful life events and inflammation among adolescents with a history of early institutional rearing.Development and psychopathology · 2020Trial
- Within-person longitudinal associations between depressive symptoms and interpersonal problems in adolescent girls.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Inflammation, fronto-amygdala connectivity, and negative affective reactivity to daily stress in adolescents.Brain, behavior, & immunity - health · 2026Article
- Being praised and criticized in adolescents and adults: Age-related changes in neural responses to social evaluations.Developmental cognitive neuroscience · 2026Article
- The topology of adolescent mental health.medRxiv : the preprint server for health sciences · 2026Article
- Risk Perception and Susceptibility to Peer Influence Predict Substance Use in Early Adolescence: Findings From the ABCD Study.Journal of studies on alcohol and drugs · 2026Article
- Parent-Child Conflict and Psychological Adjustment: The Serial Mediating Roles of Psychological Control and Basic Psychological Needs.Behavioral sciences (Basel, Switzerland) · 2026Article
- Neural responses to error in youth: the impact of social context, anxiety, and worry.European child & adolescent psychiatry · 2026Article
- Effects of sex, pubertal stage, and pubertal hormones on frontal and limbic responses to fearful and happy faces during early adolescence.Psychoneuroendocrinology · 2026Article
- Identifying neurodevelopmental signatures of worry: An ultra-high field (7-Tesla) fMRI study among adolescents and young adults.Developmental cognitive neuroscience · 2026Article
- Daily-Life Peer Interactions Among Adolescents at Familial High-Risk for Psychosis: An Ecological Momentary Assessment (EMA) Study.Child psychiatry and human development · 2026Article
- Developmental changes in youth affect: A within-person approach.Emotion (Washington, D.C.) · 2026Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Adolescents are commonly portrayed as highly emotional, with their behaviors often hijacked by their emotions. Research on the neural substrates of adolescent affective behavior is beginning to paint a more nuanced picture of how neurodevelopmental changes in brain function influence affective behavior, and how these influences are modulated by external factors in the environment. Recent neurodevelopmental models suggest that the brain is designed to promote emotion regulation, learning, and affiliation across development, and that affective behavior reciprocally interacts with age-specific social demands and different social contexts. In this review, we discuss current findings on neurobiological mechanisms of adolescents' affective behavior and highlight individual differences in and social-contextual influences on adolescents' emotionality. Neurobiological mechanisms of affective processes related to anxiety and depression are also discussed as examples. As the field progresses, it will be critical to test new hypotheses generated from the foundational empirical and conceptual work and to focus on identifying more precisely how and when neural networks change in ways that promote or thwart adaptive affective behavior during adolescence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.