Evidence map›Paper›PMID 27505443›Full record

ArticleClinical cardiology2016

Prevalence and Factors Associated With Statin Use Among a Nationally Representative Sample of US Adults: National Health and Nutrition Examination Survey, 2011-2012.

Demilade Adedinsewo, Nchang Taka, Pradyumna Agasthi, Rajesh Sachdeva, George Rust, Anekwe Onwuanyi

Open access · greenAbstract read
In one paragraph

Article in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Statins & risk ofThe Indian journal of medical research · 2019
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  16. Improvement of Statin Utilization in Veterans With Diabetes Through Pharmacy Interventions.Clinical diabetes : a publication of the American Diabetes Association · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Demilade AdedinsewoDivision of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia. dadedinsewo@msm.edu.ORCID http://orcid.org/0000-0002-8629-2029
Nchang TakaDivision of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.
Pradyumna AgasthiDivision of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.
Rajesh SachdevaDivision of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.
George RustDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, Florida.
Anekwe OnwuanyiDivision of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.
Grady Memorial Hospital · USFlorida State University · US

Funding

Research Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MAYBERRY, ROBERT M · 2012 to 2018
$24.8M
Women's Health Intervention StudyP20MD006881 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI DAVIS, SHARON K · 2012 to 2016
$6.0M
Mid-Career Transition -- Mapping Paths to Success in Achieving Community-Level HeK18HS022444 · AHRQ · MOREHOUSE SCHOOL OF MEDICINE · PI RUST, GEORGE S · 2013 to 2014
$532k
AHRQ HHS K18 HS022444NIMHD NIH HHS P20 MD006881NIMHD NIH HHS U54 MD007588
6 · The paper itself

Abstract

The 2013 American College of Cardiology/American Heart Association guidelines recommend statins for adults age ≤75 years who have clinical atherosclerotic cardiovascular disease (IA) and adults age 40 to 75 years with diabetes mellitus and LDL-C 70-189 mg/dl (IA). Our aim was to estimate the prevalence and likelihood of statin use among selected statin benefit groups. Using data from the National Health and Nutrition Examination Survey (NHANES) 2011-2012, we examined 5319 adults age ≥20 years. We estimated weighted frequencies and prevalence of statin use for adults with diabetes mellitus and dyslipidemia (or low-density lipoprotein cholesterol ≥70 mg/dL), defined as statin benefit group 1 (SBG1); and for adults with atherosclerotic cardiovascular disease, defined as statin benefit group 2 (SBG2). We constructed a logistic regression model to estimate odds of statin use in SBG1. Overall, an estimated 38.6 million Americans are on a statin. In adjusted models, uninsured and Hispanic adults were less likely to be on a statin compared with white adults; 59.5% (95% confidence interval [CI]: 53.0-66.1) of all adults in SBG1, 58.8% (95% CI: 51.5-66.1) of adults age 40 to 75 in SBG1, and 63.5% (95% CI: 55.6-71.4) of all adults in SBG2 were on a statin. Although the prevalence of statin use has increased over time, Hispanic ethnicity and lack of insurance remain barriers to statin use. Black-white racial disparities were not significant. Our study provides a baseline estimate of statin use in the noninstitutionalized population just prior to introduction of the new guidelines and provides a reference for evaluating the impact of the new guidelines on statin utilization.

Indexed as

Healthcare DisparitiesAdultAgedAge FactorsAtherosclerosisBlack or African AmericanChi-Square DistributionComorbidityDiabetes MellitusDyslipidemiasFemaleHispanic or LatinoHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLogistic ModelsMaleHydroxymethylglutaryl-CoA Reductase InhibitorsClinicalEpidemiologyLipidologyPharmacologyPreventive cardiology

Identifiers

PMID27505443
PMCPMC5030167
OpenAlexW2514514030

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.