Evidence map›Paper›PMID 27504534›Full record

Trial reportImplant dentistry2016

The Effect of Platform Switching on Periimplant Crevicular Fluid Content During Early Wound Healing.

Hua-Hong Chien, Hsiu-Wan Meng, Amy C Gross, Timothy D Eubank, Vedat O Yildiz, Binnaz Leblebicioglu

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Implant dentistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03538184 (Cytokine, Chemokine and Growth Factor Content of Peri-implant Sulcus During Wound Healing and Osseointegration After Conventional and Piezosurgical Implant Site Preparation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03538184 nacompletednot on this map

Cytokine, Chemokine and Growth Factor Content of Peri-implant Sulcus During Wound Healing and Osseointegration After Conventional and Piezosurgical Implant Site Preparation

TypeinterventionalSponsorEge UniversityRan2013 to 2015Enrolled14ConditionsTooth Loss, Edentulous JawArmsPiezosurgery, Drill
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hua-Hong Chien*Clinical Professor, Division of Periodontology, College of Dentistry, The Ohio State University, Columbus, OH. †Clinical Assistant Professor, Department of Periodontotics, School of Dentistry, University of Texas, Houston, TX. ‡Senior Research Associate, Nationwide Children's Hospital, Columbus, OH. §Associate Professor, Department of Microbiology, Immunology and Cell Biology, School of Medicine, West Virginia University, Morgantown, WV. ¶Biostatistician II, Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH. ‖Professor, Division of Periodontology, College of Dentistry, The Ohio State University, Columbus, OH.
Hsiu-Wan Meng
Amy C Gross
Timothy D Eubank
Vedat O Yildiz
Binnaz Leblebicioglu

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

purposeThe objective of this study was to investigate the soft tissue response and periimplant crevicular fluid (PICF) content around platform-switched (PS) and platform-matched (PM) implants during early healing. MATERIALS AND

methodsNonsmokers treatment planned to receive a single implant in 2 quadrants were recruited. Two-stage implant placement protocol with 1 PM and 1 PS implant was implemented. Periimplant probing depths (PDs), modified sulcus bleeding index, and plaque indices were recorded, and PICF was collected at 1, 2, 4, and 6 weeks after abutment connection.

resultsPD readings were higher at week 1 than at week 6 for both groups (P = 0.0005). PD was statistically deeper in PM than in PS at week 1 (P = 0.03). There was a time-dependent decrease in total PICF volume for both groups. This decrease was statistically significant for PS (P = 0.0005), with no differences between the 2 groups at any time (P > 0.05). The decrease observed in both PM and PS for PICF interleukin 6 and macrophage inflammatory protein-1β, and in PS for tumor necrosis factor-α (TNF-α) was statistically significant (P ≤ 0.03). TNF-α was statistically higher in PS than in PM at week 1 (P = 0.005).

conclusionWithin the limits of this study, it seems that periimplant soft tissue response around PM and PS implants is mostly similar during the early healing period.

Indexed as

Dental Implant-Abutment DesignDental ImplantsWound HealingAdultAgedCytokinesFemaleGingival Crevicular FluidHumansMaleMiddle AgedSurgical WoundCytokinesDental Implants

Identifiers

PMID27504534
PMCPMC5523451

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.