Evidence map›Paper›PMID 27504476›Full record

ReviewEuropean journal of radiology open2016

Intra-individual diagnostic image quality and organ-specific-radiation dose comparison between spiral cCT with iterative image reconstruction and z-axis automated tube current modulation and sequential cCT.

Holger Wenz, Máté E Maros, Mathias Meyer, Joshua Gawlitza, Alex Förster, Holger Haubenreisser, Stefan Kurth, Stefan O Schoenberg, Christoph Groden, Thomas Henzler

Open access · goldAbstract readReview

PubMed Full text at PMC Publisher

In one paragraph

Review in European journal of radiology open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it

0cells of the map it votes in

6citing papers in PubMed

1.1field-weighted citation impact, top 21% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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Improved Peritoneal Cavity and Abdominal Organ Imaging Using a Biphasic Contrast Agent Protocol and Spectral Photon Counting Computed Tomography K-Edge Imaging.Investigative radiology · 2018
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Automatic tube potential selection with tube current modulation in coronary CT angiography: Can it achieve consistent image quality among various individuals?Experimental and therapeutic medicine · 2018
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Cervical Selective Nerve Root Block: Three-dimensional Puncture Planning With Dyna-CT Is Superior to Conventional CT-guidance in anIn vivo (Athens, Greece)
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Holger WenzDepartment of Neuroradiology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Máté E MarosDepartment of Neuroradiology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Mathias MeyerInstitute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Joshua GawlitzaInstitute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Alex FörsterDepartment of Neuroradiology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Holger HaubenreisserInstitute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Stefan KurthDepartment of Neuroradiology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Stefan O SchoenbergInstitute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Christoph GrodenDepartment of Neuroradiology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Thomas HenzlerInstitute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.

Heidelberg University · DEUniversity Hospital Heidelberg · DEUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo prospectively evaluate image quality and organ-specific-radiation dose of spiral cranial CT (cCT) combined with automated tube current modulation (ATCM) and iterative image reconstruction (IR) in comparison to sequential tilted cCT reconstructed with filtered back projection (FBP) without ATCM.

methods31 patients with a previous performed tilted non-contrast enhanced sequential cCT aquisition on a 4-slice CT system with only FBP reconstruction and no ATCM were prospectively enrolled in this study for a clinical indicated cCT scan. All spiral cCT examinations were performed on a 3rd generation dual-source CT system using ATCM in z-axis direction. Images were reconstructed using both, FBP and IR (level 1-5). A Monte-Carlo-simulation-based analysis was used to compare organ-specific-radiation dose. Subjective image quality for various anatomic structures was evaluated using a 4-point Likert-scale and objective image quality was evaluated by comparing signal-to-noise ratios (SNR).

resultsSpiral cCT led to a significantly lower (p < 0.05) organ-specific-radiation dose in all targets including eye lense. Subjective image quality of spiral cCT datasets with an IR reconstruction level 5 was rated significantly higher compared to the sequential cCT acquisitions (p < 0.0001). Consecutive mean SNR was significantly higher in all spiral datasets (FBP, IR 1-5) when compared to sequential cCT with a mean SNR improvement of 44.77% (p < 0.0001).

conclusionsSpiral cCT combined with ATCM and IR allows for significant-radiation dose reduction including a reduce eye lens organ-dose when compared to a tilted sequential cCT while improving subjective and objective image quality.

Indexed as

ASPECTS, Alberta Stroke Program Early CT scoreATCM, automated tube current modulationAutomatic tube current modulationcCT, cranial computed tomographycCT, cranial CTDSCT, dual-source computed tomographyFBP, filtered back projectionHU, hounsfield unitsICRP, International Commission on Radiological ProtectionIR, iterative image reconstructionIterative reconstructionMDCT, multi-detector computed tomographyNC, caudate nucleusND, normally distributed dataNI, non-inferiority analysisOrgan-specific-radiation doseSequential cranial CTSNR, signal-to-noise ratiosSpiral cranial CTWM, white matter

Identifiers

PMID27504476

DOI10.1016/j.ejro.2016.05.006

PMCPMC4969238

OpenAlexW2493186718

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.