ArticleJournal of clinical and diagnostic research : JCDR2016
Transdermal Buprenorphine Patches for Postoperative Pain Control in Abdominal Surgery.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Transdermal buprenorphine for acute postoperative pain: a systematic review].Brazilian journal of anesthesiology (Elsevier)Pooled it
- Comparative study of the efficacy of transdermal buprenorphine patches and prolonged-release tramadol tablets for postoperative pain control after spinal fusion surgery: a prospective, randomized controlled non-inferiority trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017Trial
- Article
- Safety And Efficacy Of The Unique Opioid Buprenorphine For The Treatment Of Chronic Pain.Journal of pain research · 2019Review
- Efficacy of transdermal buprenorphine patch on post-operative pain relief after elective spinal instrumentation surgery.Indian journal of anaesthesia · 2017Article
- Buprenorphine for acute post-surgical pain: A systematic review and meta-analysis.Saudi journal of anaesthesiaReview
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBuprenorphine is a semi-synthetic derivative of thebaine; its low concentration is sufficient to provide effective pain relief.
aimTo evaluate the efficacy of transdermal buprenorphine patch in postoperative pain management. MATERIALS AND
methodsAfter ethical approval and taking informed consent from the patients, they were randomized into three groups (n=30 in each group) using a computer generated random number table. Group A: placebo patch; Group B: buprenorphine (10mg) patch and Group C: buprenorphine (20mg) patch. Haemodynamic and analgesic effects were compared by using analysis of variance (ANOVA) followed by Turkey's post hoc test. The proportion of side effects was compared using the Chi-square test.
resultsHaemodynamic changes were not statistically different in all the three groups A, B and C, whereas at the end of surgery VAS score of Group A subjects was significantly higher (4.93±0.98) as compared to Group B (1.73±0.64) and Group C (1.40±0.50). On 2(nd) postoperative day, no pain was reported by the Group C patients and on 4(th) day after surgery, no pain was reported by Group B patients.
conclusionThe transdermal buprenorphine patch (20mg) was effective in attenuating postoperative pain, maintaining haemodynamic stability requiring no rescue analgesia, with fewer postoperative rescue analgesic requirements in low dose of buprenorphine patch (10mg) group.
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