ArticleJournal of clinical and diagnostic research : JCDR2016
Skeletal Maturation and Mineralisation of Children with Moderate to Severe Spastic Quadriplegia.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 14 citations in OpenAlex.
- Children with brain tumors: how do they perform in academics later?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Accelerated skeletal maturation is associated with overweight and obesity as early as preschool age: a cross-sectional study.BMC pediatrics · 2020Article
- Correspondence: Skeletal Maturation and Mineralization of Children with Moderate to Severe Spastic Quadriplegia.Journal of clinical and diagnostic research : JCDR · 2017Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDiminished bone mineral density and delayed skeletal maturation are common in children with spastic quadriplegia.
aimThe purpose of our study was to evaluate the Bone Mineral Density (BMD) of children with moderate to severe spastic quadriplegia and its relationship with other variables like nutrition and growth. MATERIALS AND
methodsThis was a hospital based, cross- sectional, case-control study. Forty-two (28 males, 14 females) children with spastic quadriplegia and 42 (24 males, 18 females) healthy children were included in the study. BMD of cases and control were measured by Dual Energy X-ray Absorptiometry (DEXA). Radiographs of left hand and wrist of cases and controls were taken and bone age was determined.
resultsBMD values of upper extremity, lower extremity, thoraco-lumbar spine and pelvis in cases were lower than those of controls (p <0.0001). In children with non severe malnutrition, 75% of the cases had lower bone age than chronological age, whereas all cases with severe malnutrition had lower bone age than chronological age. Step wise regression analysis showed that nutritional status independently contributed to lower BMD values but the BMD values did not correlate significantly with the use of anticonvulsant drugs and presence of physical therapy.
conclusionDecreased BMD and delayed bone age is prevalent in children with spastic quadriplegia and nutritional status is an important contributing factor.
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