ReviewSkeletal muscle2016
Embracing change: striated-for-smooth muscle replacement in esophagus development.
Review in Skeletal muscle, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Variance expression of MUC17 and mucin histochemistry in the gastrointestinal tract of the desert-adapted Euphrates jerboa (Open veterinary journal · 2026Article
- Functional integration of an autologous engineered esophagus in a large-animal model.Nature biotechnology · 2026Article
- A mathematical model of human oesophageal motility function.Royal Society open science · 2025Article
- Morphological and Histological Analysis of the Gastrointestinal Systems inAnimals : an open access journal from MDPI · 2025Article
- Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus.Nature communications · 2024Article
- Histology and Ultrastructure of the Esophagus in European Beaver (Animals : an open access journal from MDPI · 2023Article
- Transcriptome Dynamics in the Developing Larynx, Trachea, and Esophagus.Frontiers in cell and developmental biology · 2022Article
- Developmental events and cellular changes occurred during esophageal development of quail embryos.Scientific reports · 2021Article
- Cetacean Orbital Muscles: Anatomy and Function of the Circular Layers.Anatomical record (Hoboken, N.J. : 2007) · 2020Article
- Tissue engineering of the gastroesophageal junction.Journal of tissue engineering and regenerative medicine · 2020Review
- Article
- Osr1 functions downstream of Hedgehog pathway to regulate foregut development.Developmental biology · 2017Article
- Enteric co-innervation of striated muscle in the esophagus: still enigmatic?Histochemistry and cell biology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The esophagus functions to transport food from the oropharyngeal region to the stomach via waves of peristalsis and transient relaxation of the lower esophageal sphincter. The gastrointestinal tract, including the esophagus, is ensheathed by the muscularis externa (ME). However, while the ME of the gastrointestinal tract distal to the esophagus is exclusively smooth muscle, the esophageal ME of many vertebrate species comprises a variable amount of striated muscle. The esophageal ME is initially composed only of smooth muscle, but its developmental maturation involves proximal-to-distal replacement of smooth muscle with striated muscle. This fascinating phenomenon raises two important questions: what is the developmental origin of the striated muscle precursor cells, and what are the cellular and morphogenetic mechanisms underlying the process? Studies addressing these questions have provided controversial answers. In this review, we discuss the development of ideas in this area and recent work that has shed light on these issues. A working model has emerged that should permit deeper understanding of the role of ME development and maturation in esophageal disorders and in the functional and evolutionary underpinnings of the variable degree of esophageal striated myogenesis in vertebrate species.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.