Evidence map›Paper›PMID 27504162›Full record

ArticleElectronic physician2016

The link between bone disease and cardiovascular complications in hemodialysis patients.

Noha Elsheikh, Nevine Sherif, Sameh Abou Zeid, Mervat Eldamarawy, Ahmed Ali, Amal Ismail Sabry

Open access · goldAbstract read
In one paragraph

Article in Electronic physician, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Noha ElsheikhDepartment of Nephrology, Theodor Bilharz Research Institute, Cairo, Egypt.
Nevine SherifDepartment of Nephrology, Theodor Bilharz Research Institute, Cairo, Egypt.
Sameh Abou ZeidDepartment of Nephrology, Theodor Bilharz Research Institute, Cairo, Egypt.
Mervat EldamarawyDepartment of Intensive Care Unit, Theodor Bilharz Research Institute, Cairo, Egypt.
Ahmed AliDepartment of Intensive Care Unit, Theodor Bilharz Research Institute, Cairo, Egypt.
Amal Ismail SabryDepartment of Intensive Care Unit, Theodor Bilharz Research Institute, Cairo, Egypt.
Theodor Bilharz Research Institute · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe burden on the cardiovascular system is the main cause of mortality in chronic renal patients, and bone disease, which also may cause disability, is one of the most important complications in those patients. The aim of this study was to determine the link between cardiovascular and bone disease, which frequently occur together.

methodsIn this matched case-control study, 70 subjects were subjected for full laboratory assessment as well as estimation of parathyroid hormone (PTH) level, vitamin D level, complete echocardiography, and dual energy absorptiometry. Of the 70 patients, 50 were on regular hemodialysis, and there were 20 normal controls matched with the patients with respect to age and gender.

resultsThere was a significant decrease in the mean value of serum vitamin D in the hemodialysis patients, i.e., their mean value was 20.47 ± 9.60 whereas the controls had a mean value of 37.15 ± 7.67. Thus, there was a highly-significant, negative correlation between vitamin D and left ventricular mass (LVM) in the patients. We found that there was a highly-significant increase in the mean PTH levels of the patients (820.22 ± 393.51), whereas it was 57.60 ± 13.72 for the controls. The statistical significance was less than 0.001, a highly-significant increase in the mean of the T score levels in the patients (-2.15 ± 2.56), whereas it was -0.47 ± 0.71 for the controls with a statistical significance of less than 0.001. There also was a highly-significant correlation between the T score and LVM.

conclusionA significant correlation was found between bone disease and the occurrence of a left ventricular mass. We recommend early strict correction of the serum levels of vitamin D, PTH, calcium, and phosphorus.

Indexed as

cardiovascular complicationechocardiographyhemodialysis

Identifiers

PMID27504162
PMCPMC4965197
OpenAlexW2461482208

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.