Evidence map›Paper›PMID 27504149›Full record

ReviewOxidative medicine and cellular longevity2016

"Cumulative Stress": The Effects of Maternal and Neonatal Oxidative Stress and Oxidative Stress-Inducible Genes on Programming of Atopy.

Sara Manti, Lucia Marseglia, Gabriella D'Angelo, Caterina Cuppari, Erika Cusumano, Teresa Arrigo, Eloisa Gitto, Carmelo Salpietro

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Cystic Fibrosis and Oxidative Stress: The Role of CFTR.Molecules (Basel, Switzerland) · 2022
    Review
  5. The association between prenatal FFree radical biology & medicine · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sara MantiUnit of Pediatric Genetics and Immunology, Department of Pediatrics, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-7664-3083
Lucia MarsegliaNeonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Messina, 98125 Messina, Italy.ORCID 0000-0003-0720-9387
Gabriella D'AngeloNeonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Messina, 98125 Messina, Italy.
Caterina CuppariUnit of Pediatric Genetics and Immunology, Department of Pediatrics, University of Messina, 98125 Messina, Italy.
Erika CusumanoNeonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Messina, 98125 Messina, Italy.
Teresa ArrigoUnit of Pediatric Genetics and Immunology, Department of Pediatrics, University of Messina, 98125 Messina, Italy.
Eloisa GittoNeonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Messina, 98125 Messina, Italy.
Carmelo SalpietroUnit of Pediatric Genetics and Immunology, Department of Pediatrics, University of Messina, 98125 Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although extensive epidemiological and laboratory studies have been performed to identify the environmental and immunological causes of atopy, genetic predisposition seems to be the biggest risk factor for allergic diseases. The onset of atopic diseases may be the result of heritable changes of gene expression, without any alteration in DNA sequences occurring in response to early environmental stimuli. Findings suggest that the establishment of a peculiar epigenetic pattern may also be generated by oxidative stress (OS) and perpetuated by the activation of OS-related genes. Analyzing the role of maternal and neonatal oxidative stress and oxidative stress-inducible genes, the purpose of this review was to summarize what is known about the relationship between maternal and neonatal OS-related genes and the development of atopic diseases.

Indexed as

Epigenesis, GeneticGene Expression RegulationGenetic Predisposition to DiseaseHeredityHumansHypersensitivityInfant, NewbornMaleOxidative StressPhenotypeRisk Factors

Identifiers

PMID27504149
PMCPMC4967692
OpenAlexW2492848526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.