ArticleJournal of contemporary brachytherapy2016
Dosimetric study for cervix carcinoma treatment using intensity modulated radiation therapy (IMRT) compensation based on 3D intracavitary brachytherapy technique.
Article in Journal of contemporary brachytherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- 3D-printed brachytherapy in patients with cervical cancer: improving efficacy and safety outcomes.Radiation oncology (London, England) · 2024Article
- Brachytherapy for cervical cancer: from intracavitary to interstitial technique.Frontiers in oncology · 2024Review
- Dosimetric comparison of graphical optimization and inverse planning simulated annealing for brachytherapy of cervical cancer.Journal of contemporary brachytherapy · 2019Article
- Comparative analysis of image-guided adaptive interstitial brachytherapy and intensity-modulated arc therapy versus conventional treatment techniques in cervical cancer using biological dose summation.Journal of contemporary brachytherapy · 2019Article
- IMRT and brachytherapy comparison in gynaecological cancer treatment: thinking over dosimetry and radiobiology.Ecancermedicalscience · 2019Article
- Error analysis of applicator position for combined internal/external radiation therapy in cervical cancer.Oncology letters · 2018Article
- Reduction of applicator displacement in MR/CT-guided cervical cancer HDR brachytherapy by the use of patient hover transport system.Journal of contemporary brachytherapy · 2018Article
- Comparison of dose volume parameters evaluated using three forward planning - optimization techniques in cervical cancer brachytherapy involving two applicators.Journal of contemporary brachytherapy · 2017Article
- Automated calculation of point A coordinates for CT-based high-dose-rate brachytherapy of cervical cancer.Journal of contemporary brachytherapy · 2017Article
- Optimal bladder filling during high-dose-rate intracavitary brachytherapy for cervical cancer: a dosimetric study.Journal of contemporary brachytherapy · 2017Article
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7 authors.
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Abstract
purposeIntensity modulated radiation therapy (IMRT) compensation based on 3D high-dose-rate (HDR) intracavitary brachytherapy (ICBT) boost technique (ICBT + IMRT) has been used in our hospital for advanced cervix carcinoma patients. The purpose of this study was to compare the dosimetric results of the four different boost techniques (the conventional 2D HDR intracavitary brachytherapy [CICBT], 3D optimized HDR intracavitary brachytherapy [OICBT], and IMRT-alone with the applicator in situ). MATERIAL AND
methodsFor 30 patients with locally advanced cervical carcinoma, after the completion of external beam radiotherapy (EBRT) for whole pelvic irradiation 45 Gy/25 fractions, five fractions of ICBT + IMRT boost with 6 Gy/fractions for high risk clinical target volume (HRCTV), and 5 Gy/fractions for intermediate risk clinical target volume (IRCTV) were applied. Computed tomography (CT) and magnetic resonance imaging (MRI) scans were acquired using an in situ CT/MRI-compatible applicator. The gross tumor volume (GTV), the high/intermediate-risk clinical target volume (HRCTV/IRCTV), bladder, rectum, and sigmoid were contoured by CT scans.
resultsFor ICBT + IMRT plan, values of D90, D100 of HRCTV, D90, D100, and V100 of IRCTV significantly increased (p < 0.05) in comparison to OICBT and CICBT. The D2cc values for bladder, rectum, and sigmoid were significantly lower than that of CICBT and IMRT alone. In all patients, the mean rectum V60 Gy values generated from ICBT + IMRT and OICBT techniques were very similar but for bladder and sigmoid, the V60 Gy values generated from ICBT + IMRT were higher than that of OICBT. For the ICBT + IMRT plan, the standard deviations (SD) of D90 and D2cc were found to be lower than other three treatment plans.
conclusionsThe ICBT + IMRT technique not only provides good target coverage but also maintains low doses (D2cc) to the OAR. ICBT + IMRT is an optional technique to boost parametrial region or tumor of large size and irregular shape when intracavitary/interstitial brachytherapy cannot be used.
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