ArticleDementia and geriatric cognitive disorders extra
The Diagnostic Utility of the NINDS-CSN Neuropsychological Battery in Memory Clinics.
Article in Dementia and geriatric cognitive disorders extra. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
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- Longitudinal associations of carotid artery stiffness with progression of cerebrovascular disease, incident dementia and cognitive decline in older adults.The journal of prevention of Alzheimer's disease · 2025Article
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- Diagnosis of cognitive impairment and dementia: blood plasma and optical coherence tomography.Brain communications · 2025Article
- Interactive effect of diabetes mellitus and subclinical MRI markers of cerebrovascular disease on cognitive decline and incident dementia: a memory-clinic study.Alzheimer's research & therapy · 2024Article
- Independent and joint associations of cardiometabolic multimorbidity and depression on cognitive function: findings from multi-regional cohorts and generalisation from community to clinic.The Lancet regional health. Western Pacific · 2024Article
- Elevated Soluble TNF-Receptor 1 in the Serum of Predementia Subjects with Cerebral Small Vessel Disease.Biomolecules · 2023Article
- Teleneuropsychology for vascular cognitive impairment: Which tools do we have?Cerebral circulation - cognition and behavior · 2023Review
- Effects of Carotid Artery Stiffness on Cerebral Small-Vessel Disease and Cognition.Journal of the American Heart Association · 2022Article
- Low Plasma Ergothioneine Predicts Cognitive and Functional Decline in an Elderly Cohort Attending Memory Clinics.Antioxidants (Basel, Switzerland) · 2022Article
- Deep-learning retinal vessel calibre measurements and risk of cognitive decline and dementia.Brain communications · 2022Article
- The discriminant validity of single-question assessments of subjective cognitive complaints in an Asian older adult population.Frontiers in aging neuroscience · 2022Article
- Improved amyloid burden quantification with nonspecific estimates using deep learning.European journal of nuclear medicine and molecular imaging · 2021Article
- Cortical cerebral microinfarcts predict cognitive decline in memory clinic patients.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Article
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Authors and funding
9 authors.
Funding
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Abstract
aimsTo examine the diagnostic utility of the National Institute of Neurological Disorders and Stroke and the Canadian Stroke Network (NINDS-CSN) neuropsychological battery in memory clinics comparing controls with patients with no cognitive impairment (NCI), patients with cognitive impairment-no dementia (CIND) at varying severity levels (mild/moderate), and patients with dementia.
methodsA total of 405 participants with NCI, CIND or dementia were assessed with the NINDS-CSN battery. The discriminatory properties of all three protocols (5, 30 and 60 min) before and after education stratification (none/primary vs. secondary/above) were examined by receiver operating characteristic curves.
resultsOverall, the shorter protocols are equivalent to the longer protocol in diagnosing dementia, regardless of education. To discriminate between nondementia groups, before education stratification, the 5-min protocol showed varied discriminatory properties between different diagnostic/severity groups. After stratification, the 5-min protocol was broadly equivalent to the longer protocols in lower-education groups [area under the curve (AUC) range: 0.77-0.87] but was less accurate in the higher-education groups (AUC range: 0.68-0.78). The 30- and 60-min protocol constantly showed moderate-to-excellent differentiating capacities regardless of education (AUC range: 0.80-0.90).
conclusionThe NINDS-CSN neuropsychological battery can be applied in memory clinics and effectively discriminate between cognitively intact individuals and those with cognitive impairments of varying severity. Furthermore, level of education should be taken into consideration when choosing protocols with different lengths for cognitive assessment.
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