ArticleFrontiers in neurology2016
Functional Connectivity Is Altered in Concussed Adolescent Athletes Despite Medical Clearance to Return to Play: A Preliminary Report.
Article in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Drivers of resting-state fMRI heterogeneity in traumatic brain injury across injury characteristics and imaging methods: a systematic review and semiquantitative analysis.Frontiers in neurology · 2024Pooled it
- Advanced biomarkers of pediatric mild traumatic brain injury: Progress and perils.Neuroscience and biobehavioral reviews · 2018Pooled it
- A systematic review of criteria used to define recovery from sport-related concussion in youth athletes.British journal of sports medicine · 2018Pooled it
- The impact of an app-delivered mindfulness-based intervention on resting-state functional connectivity in pediatric concussion: a pilot study.Frontiers in neuroscience · 2026Trial
- Memory outcomes and interventions after sports-related traumatic brain injuries in pediatric and young adult athletes: a scoping review.Journal of pediatric psychology · 2025Article
- Linking a Deep Learning Model for Concussion Classification with Reorganization of Large-Scale Brain Networks in Female Youth.Bioengineering (Basel, Switzerland) · 2025Article
- High-magnitude headers are not associated with structural and functional brain changes in active high-level football (soccer) players.BMJ open sport & exercise medicine · 2025Article
- Patterns of Change in Functional Connectivity and Motor Performance Are Different in Youth Recently Recovered from Concussion.Neurotrauma reports · 2025Article
- Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated concussions.Journal of neurology · 2024Article
- Article
- The effects of sports-related concussion history on female adolescent brain activity and connectivity for bilateral lower extremity knee motor control.Psychophysiology · 2023Article
- Sex-specific differences in resting-state functional brain activity in pediatric concussion.Scientific reports · 2023Article
- Investigating the diagnostic accuracy of a paper-and-pencil and a computerized cognitive test battery for pediatric mild traumatic brain injury.Neuropsychology · 2022Article
- No Evidence of a Difference in Susceptibility-Weighted Imaging Lesion Burden or Functional Network Connectivity between Children with Typical and Delayed Recovery Two Weeks Post-Concussion.Journal of neurotrauma · 2021Observational
- Recurrent neural network-based acute concussion classifier using raw resting state EEG data.Scientific reports · 2021Article
- Deep Learning Recurrent Neural Network for Concussion Classification in Adolescents Using Raw Electroencephalography Signals: Toward a Minimal Number of Sensors.Frontiers in human neuroscience · 2021Article
- Evidence of early vasogenic edema following minor head impact that can be reduced with a vasopressin V1a receptor antagonist.Brain research bulletin · 2020Article
- A Dose Relationship Between Brain Functional Connectivity and Cumulative Head Impact Exposure in Collegiate Water Polo Players.Frontiers in neurology · 2020Article
- Persistent Disruption of Brain Connectivity after Sports-Related Concussion in a Female Athlete.Journal of neurotrauma · 2019Article
- Treatments and rehabilitation in the acute and chronic state of traumatic brain injury.Journal of internal medicine · 2019Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Recovery following sports-related concussion (SRC) is slower and often more complicated in young adolescent athletes than in collegiate players. Further, the clinical decision to return to play is currently based on symptoms and cognitive performance without direct knowledge of brain function. We tested the hypothesis that brain functional connectivity (FC) would be aberrant in recently concussed, asymptomatic athletes who had been cleared to return to play. A seed-based FC analysis measured the FC of the default mode network (DMN) (seeds = anterior cingulate cortex, posterior cingulate cortex (PCC), right lateral parietal cortex, and left lateral parietal cortex) 30 days after SRC in asymptomatic high school athletes cleared to return to play (n = 13) and was compared to the FC of high school athletes with orthopedic injury (OI) (n = 13). The SRC group demonstrated greater FC than the OI group between the PCC and the ventral lateral prefrontal cortex, as well as between the right lateral parietal cortex and lateral temporal cortex (with regions both outside of and within the DMN). Additionally, the OI group demonstrated greater FC than the SRC group between right lateral parietal cortex and supramarginal gyrus. When relating the FC results to verbal memory performance approximately 1 week and 1 month after injury, significantly different between-group relations were found for the posterior cingulate and right lateral parietal cortex seeds. However, the groups did not differ in verbal memory at 1 month. We suggest that changes in FC are apparent 1-month post-SRC despite resolution of post-concussion symptoms and recovery of cognitive performance in adolescent athletes cleared to return to play.
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