Evidence map›Paper›PMID 27503959›Full record

ReviewHealth affairs (Project Hope)2016

Using Genetic Technologies To Reduce, Rather Than Widen, Health Disparities.

Caren E Smith, Stephanie M Fullerton, Keith A Dookeran, Heather Hampel, Adrienne Tin, Nisa M Maruthur, Jonathan C Schisler, Jeffrey A Henderson, Katherine L Tucker, José M Ordovás

Registry-linked trialAbstract readReview
In one paragraph

Review in Health affairs (Project Hope), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01231958 (The Boston Puerto Rican Health Study), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01231958 completednot on this map

The Boston Puerto Rican Health Study: Center for Population Health and Health Disparities

TypeobservationalSponsorUniversity of Massachusetts, LowellRan2004 to 2017Enrolled1,650ConditionsCardiovascular Risk FactorArmsThe Heart Healthy Initiative for Hispanic Adults (HIP)
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Polygenic risk, population structure and ongoing difficulties with race in human genetics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caren E SmithCaren E. Smith (caren.smith@tufts.edu) is a scientist in the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, in Boston, Massachusetts.
Stephanie M FullertonStephanie M. Fullerton is an associate professor in the Department of Bioethics and Humanities at the University of Washington, in Seattle.
Keith A DookeranKeith A. Dookeran is an assistant professor in the Division of Epidemiology and Biostatistics, School of Public Health, at the University of Illinois at Chicago and chair and CEO of the Cancer Foundation for Minority and Underserved Populations, also in Chicago.
Heather HampelHeather Hampel is a professor in the Division of Human Genetics at the Ohio State University Comprehensive Cancer Center, in Columbus.
Adrienne TinAdrienne Tin is an assistant scientist in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health, in Baltimore, Maryland.
Nisa M MaruthurNisa M. Maruthur is an assistant professor in the Division of General Internal Medicine at the Johns Hopkins University School of Medicine, the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health, and the Welch Center for Prevention, Epidemiology, and Clinical Research at Johns Hopkins University.
Jonathan C SchislerJonathan C. Schisler is an assistant professor in the Department of Pharmacology at the University of North Carolina at Chapel Hill.
Jeffrey A HendersonJeffrey A. Henderson is president and CEO of the Black Hills Center for American Indian Health, in Rapid City, South Dakota.
Katherine L TuckerKatherine L. Tucker is a professor in clinical laboratory and nutritional sciences at the University of Massachusetts, in Lowell.
José M OrdovásJosé M. Ordovás is director of the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

Funding

UIC CENTERS FOR POPULATION HEALTH AND HEALTH DISPARITIESP50CA106743 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WARNECKE, RICHARD · 2003 to 2016
$19.3M
TRAINING AND CAREER DEVELOPMENTP50CA105632 · NCI · OHIO STATE UNIVERSITY · PI PASKETT, ELECTRA D. · 2003 to 2016
$17.2M
Washington University Center for Diabetes Translation Research P30DK092950 · NIDDK · WASHINGTON UNIVERSITY · PI Ross C Brownson, Debra Haire-Joshu · 2011 to 2026
$11.7M
TRAINING AND CAREER DEVELOPMENTP50CA148596 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI SORENSEN, GLORIAN C · 2010 to 2014
$10.7M
STRESS MEASURES/PSYCHOMETRICSP50HL105189 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI POWELL, LYNDA H · 2010 to 2014
$10.5M
STATISTICSP50HL105185 · NHLBI · UNIVERSITY OF MASSACHUSETTS LOWELL · PI ORDOVAS, JOSE M. · 2010 to 2015
$10.4M
REDUCING DISPARITIES IN HYPERTENSION WITH A PRACTICE-BASED ENHANCED CARE PROGRAMP50HL105184 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AMMERMAN, ALICE S · 2010 to 2014
$10.1M
Vascular function, cardiovascular disease biomarkers and the Latino paradoxP50HL105188 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KAPLAN, ROBERT M · 2010 to 2014
$9.9M
TRAINING COREP50HL105187 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GOLDEN, SHERITA HILL · 2010 to 2014
$9.8M
Understanding and preventing breast cancer disparties in LatinasP50CA148143 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMPSON, BETI · 2010 to 2016
$9.7M
USING DIGITAL STORIES TO IMPROVE COLORECTAL CANCER SCREENING IN NATIVE AMERICANSP50CA148110 · NCI · UNIVERSITY OF WASHINGTON · PI GONZALES, ANGELA A · 2010 to 2014
$9.7M
RENAL DISEASE EPIDEMIOLOGY TRAINING GRANTT32DK007732 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 1995 to 2024
$7.7M
NCI NIH HHS P50 CA105632NCI NIH HHS P50 CA106743NCI NIH HHS P50 CA148110NCI NIH HHS P50 CA148143NCI NIH HHS P50 CA148596NCI NIH HHS U54 CA153498NHLBI NIH HHS K08 HL112845NHLBI NIH HHS P50 HL105184NHLBI NIH HHS P50 HL105185NHLBI NIH HHS P50 HL105187NHLBI NIH HHS P50 HL105188NHLBI NIH HHS P50 HL105189NIDDK NIH HHS P30 DK092950NIDDK NIH HHS T32 DK007732
6 · The paper itself

Abstract

Evidence shows that both biological and nonbiological factors contribute to health disparities. Genetics, in particular, plays a part in how common diseases manifest themselves. Today, unprecedented advances in genetically based diagnoses and treatments provide opportunities for personalized medicine. However, disadvantaged groups may lack access to these advances, and treatments based on research on non-Hispanic whites might not be generalizable to members of minority groups. Unless genetic technologies become universally accessible, existing disparities could be widened. Addressing this issue will require integrated strategies, including expanding genetic research, improving genetic literacy, and enhancing access to genetic technologies among minority populations in a way that avoids harms such as stigmatization.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesBlack or African AmericanBreast NeoplasmsFemaleGenetic Diseases, InbornGenetic TestingHispanic or LatinoHumansMaleMinority GroupsNeeds AssessmentRenal Insufficiency, ChronicRisk AssessmentSocioeconomic FactorsUnited StatesDeterminants Of HealthDisparitiesMinority HealthPublic HealthResearch And Technology

Identifiers

PMID27503959
PMCPMC5100696

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.