Evidence map›Paper›PMID 27503648›Full record

ArticleAntimicrobial agents and chemotherapy2016

IMP-27, a Unique Metallo-β-Lactamase Identified in Geographically Distinct Isolates of Proteus mirabilis.

Nyssa Dixon, Randal C Fowler, A Yoshizumi, Tsukasa Horiyama, Y Ishii, Lucas Harrison, Chelsie N Geyer, Ellen Smith Moland, Kenneth Thomson, Nancy D Hanson

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Clinical microbiology reviews · 2025
    Review
  3. Review
  4. Review
  5. Performance evaluation of the Streck ARM-DJournal of global antimicrobial resistance · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Emergence ofmSphere · 2021
    Article
  12. Article
  13. Profile of Enterobacteria Resistant to Beta-Lactams.Antibiotics (Basel, Switzerland) · 2020
    Article
  14. The Brief Case: IMP, the Uncommonly Common Carbapenemase.Journal of clinical microbiology · 2020
    Article
  15. Review
  16. blaClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Nyssa DixonCreighton University School of Medicine, Department of Medical Microbiology and Immunology, Center for Research in Anti-Infectives and Biotechnology, Omaha, Nebraska, USA.
Randal C FowlerDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
A YoshizumiSchool of Medical Technology, Gumma Paz College, Takasakishi, Gumma, Japan.
Tsukasa HoriyamaShionogi & Co., Ltd., Osaka, Japan.
Y IshiiToho University School of Medicine, Department of Microbiology and Infectious Diseases, Tokyo, Japan.
Lucas HarrisonCreighton University School of Medicine, Department of Medical Microbiology and Immunology, Center for Research in Anti-Infectives and Biotechnology, Omaha, Nebraska, USA.
Chelsie N GeyerCreighton University School of Medicine, Department of Medical Microbiology and Immunology, Center for Research in Anti-Infectives and Biotechnology, Omaha, Nebraska, USA.
Ellen Smith MolandCHI Health, Omaha, Nebraska, USA.
Kenneth ThomsonUniversity of Louisville School of Medicine, Louisville, Kentucky, USA.
Nancy D HansonCreighton University School of Medicine, Department of Medical Microbiology and Immunology, Center for Research in Anti-Infectives and Biotechnology, Omaha, Nebraska, USA ndhanson@creighton.edu.
Creighton University · USCHI Health · USGumma Paz College · JPShionogi (Japan) · JPToho University · JPUniversity of Louisville · USUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel metallo-β-lactamase gene, blaIMP-27, was identified in unrelated Proteus mirabilis isolates from two geographically distinct locations in the United States. Both isolates harbor blaIMP-27 as part of the first gene cassette in a class 2 integron. Antimicrobial susceptibility testing indicated susceptibility to aztreonam, piperacillin-tazobactam, and ceftazidime but resistance to ertapenem. However, hydrolysis assays indicated that ceftazidime was a substrate for IMP-27.

Indexed as

Aztreonambeta-Lactamasesbeta-LactamsCeftazidimeDrug Resistance, BacterialErtapenemHydrolysisIntegronsMicrobial Sensitivity TestsPenicillanic AcidPiperacillinPiperacillin, Tazobactam Drug CombinationProteus InfectionsProteus mirabilisUnited StatesAztreonambeta-Lactamasesbeta-LactamsCeftazidimeErtapenemPenicillanic AcidPiperacillinPiperacillin, Tazobactam Drug Combination

Identifiers

PMID27503648
PMCPMC5038328
OpenAlexW2510570509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.